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Protein
Submitted name:

ACV synthetase

Gene

pcbAB

Organism
Penicillium chrysogenum (Penicillium notatum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
ACV synthetaseImported
Gene namesi
Name:pcbABImported
OrganismiPenicillium chrysogenum (Penicillium notatum)Imported
Taxonomic identifieri5076 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaePenicilliumPenicillium chrysogenum species complex

Structurei

3D structure databases

ProteinModelPortaliA6N339.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini853 – 924CarrierInterPro annotationAdd BLAST72
Domaini1939 – 2008CarrierInterPro annotationAdd BLAST70
Domaini3028 – 3095CarrierInterPro annotationAdd BLAST68

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR010071. AA_adenyl_domain.
IPR029058. AB_hydrolase.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
IPR001031. Thioesterase.
PfamiView protein in Pfam
PF00501. AMP-binding. 3 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 3 hits.
PF00550. PP-binding. 3 hits.
PF00975. Thioesterase. 1 hit.
SMARTiView protein in SMART
SM00823. PKS_PP. 3 hits.
SUPFAMiSSF47336. SSF47336. 3 hits.
SSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 3 hits.
PROSITEiView protein in PROSITE
PS50075. ACP_DOMAIN. 3 hits.
PS00455. AMP_BINDING. 3 hits.
PS00012. PHOSPHOPANTETHEINE. 3 hits.

Sequencei

Sequence statusi: Complete.

A6N339-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQLKPPNGT TPIGFSATTS LNASGSSSVK NGTIKPSNGI FKPSTRDTMD
60 70 80 90 100
PCSGNAADGS IRVRFRGGIE RWKECVNQVP ERCDLSGLTT DSTRYQLAST
110 120 130 140 150
GFGDASAAYQ ERLMTVPVDV HAALQELCLE RRVSVGSVIN FSVHQMLKGF
160 170 180 190 200
GNGTHTITAS LHREQNLQNS SPSWVVSPTI VTHENRDGWS VAQAVESIEA
210 220 230 240 250
ARGSEKESVT AIDSASSLVK MGLFDLLVSF VDADDARIPC FDFPLAVIVR
260 270 280 290 300
ECDANLSLTL RFSDCLFNEE TICNFTDALN ILLAEAVIGR VTPVADIELL
310 320 330 340 350
SAEQKQQLEE WNNTDGEYPS SKRLHHLIEE VVERHEDKIA VVCDERELTY
360 370 380 390 400
GELNAQGNSL ARYLRSIGIL PEQLVALFLD KSEKLIVTIL GVWKSGAAYV
410 420 430 440 450
PIDPTYPDER VRFVLDDTKA RAIIASNQHV ERLQREVIGD RNLCIIRLEP
460 470 480 490 500
LLASLAQDSS KFPAHNLDDL PLTSQQLAYV TYTSGTTGFP KGIFKQHTNV
510 520 530 540 550
VNSITDLSAR YGVAGQHHEA ILLFSACVFE PFVRQTLMAL VNGHLLAVIN
560 570 580 590 600
DVEKYDADTL LPFIRRHSIT YLNGTASVLQ EYDFSDCPSL NRIILVGENL
610 620 630 640 650
TEARYLALRQ RFKNRILNEY GFTESAFVTA LKIFDPESTR KDTSLGRPVR
660 670 680 690 700
NVKCYILNPS LKRVPIGATG ELHIGGLGIS KGYLNRPELT PHRFIPNPFQ
710 720 730 740 750
TDCEKQLGIN SLMYKTGDLA RWLPNGEVEY LGRADFQIKL RGIRIEPGEI
760 770 780 790 800
ETMLAMYPRV RTSLVVSKKL RNGPEETTNE HLVGYYVCDS ASVSEADLLS
810 820 830 840 850
FLEKKLPRYM IPTRLVQLSQ IPVNVNGKAD LRALPAVDIS NSTEVRSDLR
860 870 880 890 900
GDTEIALGEI WADVLGARQR SVSRNDNFFR LGGHSITCIQ LIARIRQRQR
910 920 930 940 950
LSVSISVEDV FATRTLERMA DLLQNKQQEK CDKPHEAPTE LLEENAATDN
960 970 980 990 1000
IYLANSLQQG FVYHYLKSME QSDAYVMQSV LRYNTTLSPD LFQRAWKHAQ
1010 1020 1030 1040 1050
QSFPALRLRF SWEKEVFQLL DQDPPLDWRF LYFTDVAAGA VEDRKLEDLR
1060 1070 1080 1090 1100
RQDLTERFKL DVGRLFRVYL IKHSENRFTC LFSCHHAILD GWSLPLLFEK
1110 1120 1130 1140 1150
VHETYLQLLH GDNLTSSMDD PYTRTQRYLH AHREDHLDFW AGVVQKINER
1160 1170 1180 1190 1200
CDMNALLNER SRYKVQLADY DQVQEQRQLT IALSGDAWLA DLRQTCSAQG
1210 1220 1230 1240 1250
ITLHSILQFV WHAVLHAYGG GTHTITGTTI SGRNLPILGI ERAVGPYINT
1260 1270 1280 1290 1300
LPLVLDHSTF KDKTIMEAIE DVQAKVNVMN SRGNVELGRL HKTDLKHGLF
1310 1320 1330 1340 1350
DSLFVLENYP NLDKSRTLEH QTELGYSIEG GTEKLNYPLA VIAREVETTG
1360 1370 1380 1390 1400
GFTVSICYAS ELFEEVMISE LLHMVQDTLM QVARGLNEPV GSLEYLSSIQ
1410 1420 1430 1440 1450
LEQLAAWNAT EAEFPDTTLH EMFENEASQK PDKIAVVYEE TSLTYRELNE
1460 1470 1480 1490 1500
RANRMAHQLR SDVSPNPNEV IALVMDKSEH MIVNILAVWK SGGAYVPIDP
1510 1520 1530 1540 1550
GYPNDRIQYI LEDTQALAVI ADSCYLPRIK GMAASGTLLY PSVLPANPDS
1560 1570 1580 1590 1600
KWSVSNPSPL SRSTDLAYII YTSGTTGRPK GVTVEHHGVV NLQVSLSKVF
1610 1620 1630 1640 1650
GLRDTDDEVI LSFSNYVFDH FVEQMTDAIL NGQTLLVLND GMRGDKERLY
1660 1670 1680 1690 1700
RYIEKNRVTY LSGTPSVVSM YEFSRFKDHL RRVDCVGEAF SEPVFDKIRE
1710 1720 1730 1740 1750
TFHGLVINGY GPTEVSITTH KRLYPFPERR MDKSIGQQVH NSTSYVLNED
1760 1770 1780 1790 1800
MKRTPIGAVG ELYLGGEGVV RGYHNRADVT AERFIPNPFQ SEEDKREGRN
1810 1820 1830 1840 1850
SRLYKTGDLV RWIPGSSGEV EYLGRNDFQV KIRGLRIEVG EIEAILSSYH
1860 1870 1880 1890 1900
GIKQSVVIAK DCREGAQKFL VGYYVADAAL PSAAIRRFMQ SRLPGYMVPS
1910 1920 1930 1940 1950
RLILVSKFPV TPSGKLDTKA LPPAEEESEI DVVPPRSEIE RSLCDIWAEL
1960 1970 1980 1990 2000
LEMHPEEIGI YSDFFSLGGD SLKSTKLSFM IHESFNRAVS VSALFCHRTV
2010 2020 2030 2040 2050
EAQTHLILND AADVHEITPI DCNDTQMIPV SRAQERLLFI HEFENGSNAY
2060 2070 2080 2090 2100
NIDAAFELPG SVDASLLEQA LRGNLARHEA LRTLLVKDHA TGIYLQKVLS
2110 2120 2130 2140 2150
PDEAQGMFSV NVDTAKQVER LDQEIASLSQ HVFRLDDELP WEARILKLES
2160 2170 2180 2190 2200
GGLYLILAFH HTCFDAWSLK VFEQELRALY AALQKTKSAA NLPALKAQYK
2210 2220 2230 2240 2250
EYALYHRRQL SGDRMRNLSD FWLRKLIGLE PLQLITDRPR PVQFKYDGDD
2260 2270 2280 2290 2300
LSIELSKKET ENLRGVAKRC KSSLYVVLVS VYCVMLASYA NQSDVSVGIP
2310 2320 2330 2340 2350
VSHRTHPQFQ SVIGFFVNLV VLRVDISQSA ICGLIRRVMK ELVDAQLHQD
2360 2370 2380 2390 2400
MPFQEVTKLL QVDNDPSRHP LVQNVFNFES RANGEHDARS EDEGSLAFNQ
2410 2420 2430 2440 2450
YRPVQPVDSV AKFDLNATVT ELESGLRVNF NYATSLFNKS TIQGFLHTYE
2460 2470 2480 2490 2500
YLLRQLSELS AEGINEDTQL SLVRPTENGD LHLPLAQSPL ATTAEEQKVA
2510 2520 2530 2540 2550
SLNQAFEREA FLAAEKIAVV QGDRALSYAD LNGQANQLAR YIQSVSCIGA
2560 2570 2580 2590 2600
DDGIALMLEK SIDTIICILA IWKAGAAYVP LDPTYPPGRV QLILEEIKAK
2610 2620 2630 2640 2650
AVLVHSSHAS KCERHGAKVI AVDSPAIETA VSQQSAADLP TIASLGNLAY
2660 2670 2680 2690 2700
IIFTSGTSGK PKGVLVEQKA VLLLRDALRE RYFGRDCTKH HGVLFLSNYV
2710 2720 2730 2740 2750
FDFSVEQLVL SVLSGHKLIV PPAEFVADDE FYRMASTHGL SYLSGTPSLL
2760 2770 2780 2790 2800
QKIDLARLDH LQVVTAAGEE LHATQYEKMR RRFNGPIYNA YGVTETTVYN
2810 2820 2830 2840 2850
IIAEFTTNSI FENALREVLP GTRAYVLNAA LQPVPFDAVG ELYLAGDTVT
2860 2870 2880 2890 2900
RGYLNQPLLT DQRFIPNPFC KEEDIAMGRF ARLYKTGDLV RSRFNRQQQP
2910 2920 2930 2940 2950
QLEYLGRGDL QIKMRGYRIE ISEVQNVLTS SPGVREGAVV AKYENNDTYS
2960 2970 2980 2990 3000
RTAHSLVGYY TTDNETVSEA DILTFMKARL PTYMVPSHLC CLEGALPVTI
3010 3020 3030 3040 3050
NGKLDVRRLP EIINDSAQSS YSPPRNIIEA KMCRLWESAL GMERCGIDDD
3060 3070 3080 3090 3100
LFKLGGDSIT SLHLVAQIHN QVGCKITVRD IFEHRTARAL HDHVFMKDSD
3110 3120 3130 3140 3150
RSNVTQFRTE QGPVIGEAPL LPIQDWFLSK ALQHPMYWNH TFYVRTPELD
3160 3170 3180 3190 3200
VDSLSAAVRD LQQYHDVFRM RLKREEVGFV QSFAEDFSPA QLRVLNVKDV
3210 3220 3230 3240 3250
DGSAAVNEIL DGWQSGFNLE NGPIGSIGYL HGYEDRSARV WFSVHHMAID
3260 3270 3280 3290 3300
TVSWQILVRD LQTLYRNGSL GSKGSSFRQW AEAIQNYKAS DSERNHWNKL
3310 3320 3330 3340 3350
VMETASSISA LPTSTGSRVR LSRSLSPEKT ASLIQGGIDR QDVSVYDSLL
3360 3370 3380 3390 3400
TSVGLALQHI APTGPSMVTI EGHGREEVDQ TLDVSRTMGW FTTMYPFEIP
3410 3420 3430 3440 3450
RLSTENIVQG VVAVSERFRQ VPARGVGYGT LYGYTQHPLP QVTVNYLGQL
3460 3470 3480 3490 3500
ARKQSKPKEW VLAVGDNEFE YGLMTSPEDK DRSSSAVDVT AVCIDGTMII
3510 3520 3530 3540 3550
DVDSAWSLEE SEQFISSIEE GLNKILDGRA SQQTSRFPDV PQPAETYTPY
3560 3570 3580 3590 3600
FEYLEPPRQG PTLFLLPPGE GGAESYFNNI VKRLRQTNMV VFNNYYLHSK
3610 3620 3630 3640 3650
RLRTFEELAE MYLDQVRGIQ PHGPYHFIGW SFGGILAMEM SRRLVASDEK
3660 3670 3680 3690 3700
IGFLGIIDTY FNVRGATRTI GLGDTEILDP IHHIYNPDPA NFQRLPSATD
3710 3720 3730 3740 3750
RIVLFKAMRP NNKYESENQR RLYEYYDALD STDWTACYQA IPTSSWSRLR
3760 3770 3780 3790
TIHTFPGSEI HNRWSRCVRL SRNTSLAIDP SLAAQYIGRW K
Length:3,791
Mass (Da):425,950
Last modified:July 24, 2007 - v1
Checksum:iD56D523E3CC32B54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF601124 Genomic DNA. Translation: ABR12615.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF601124 Genomic DNA. Translation: ABR12615.1.

3D structure databases

ProteinModelPortaliA6N339.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR010071. AA_adenyl_domain.
IPR029058. AB_hydrolase.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR001242. Condensatn.
IPR020806. PKS_PP-bd.
IPR009081. PP-bd_ACP.
IPR006162. Ppantetheine_attach_site.
IPR001031. Thioesterase.
PfamiView protein in Pfam
PF00501. AMP-binding. 3 hits.
PF13193. AMP-binding_C. 2 hits.
PF00668. Condensation. 3 hits.
PF00550. PP-binding. 3 hits.
PF00975. Thioesterase. 1 hit.
SMARTiView protein in SMART
SM00823. PKS_PP. 3 hits.
SUPFAMiSSF47336. SSF47336. 3 hits.
SSF53474. SSF53474. 1 hit.
TIGRFAMsiTIGR01733. AA-adenyl-dom. 3 hits.
PROSITEiView protein in PROSITE
PS50075. ACP_DOMAIN. 3 hits.
PS00455. AMP_BINDING. 3 hits.
PS00012. PHOSPHOPANTETHEINE. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiA6N339_PENCH
AccessioniPrimary (citable) accession number: A6N339
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: May 10, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.