Reviewed, UniProtKB/Swiss-Prot A6MN00 (NU1C_ILLOL)

Names and origin

Protein names

Recommended name:
    NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic
    EC=1.6.5.-
Alternative name(s):
    NAD(P)H dehydrogenase subunit 1
      Short name=NDH subunit 1
    NADH-plastoquinone oxidoreductase subunit 1

Gene names

Name:

ndhA

Encoded on

Plastid; Chloroplast

Organism

Illicium oligandrum (Star anise)

Taxonomic identifier

145286 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › basal Magnoliophyta › Austrobaileyales › Schisandraceae › Illicium

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity.
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01350
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the complex I subunit 1 family.

Ontologies

Keywords
Cellular component	Chloroplast Membrane Plastid Thylakoid
Domain	Transmembrane
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: HAMAP
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 364	364	NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic HAMAP MF_01350		PRO_0000298871
Regions
	Transmembrane	27 – 47	21	Potential
	Transmembrane	98 – 118	21	Potential
	Transmembrane	127 – 147	21	Potential
	Transmembrane	255 – 275	21	Potential
	Transmembrane	301 – 321	21	Potential
	Transmembrane	337 – 357	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	A6MN00-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: F1A22A939AD8783D	FASTA	364	39,897
	10 20 30 40 50 60 MIIDTTEVQA INSFSRSESS KEFYGLIWLL VPIFTPVSGI LIGVLVIVWL EREISAGIQQ 70 80 90 100 110 120 RIGPEYAGPL GILQALADGT KLLFKEDLLP SRGDIRLFSV GPSIAVISIL LSYSVIPFGY 130 140 150 160 170 180 RLIIADISIG VFLWIAISSI APIGLLMSGY GSNNKYSFSG GLRAAAQSIS YEIPLTPCVL 190 200 210 220 230 240 SISLRLSNSS STVDIVEAQS KYGFCGWNLW RQPIGFIVFL ISSLAECERL PFDLPEAEEE 250 260 270 280 290 300 LVAGYQTEYS GIKSGLFYVA SYLNLLVSSL FVTVLYLGGW NLSIPYISIP ELFGINKTGG 310 320 330 340 350 360 VFGSTIGILI TLAKAYLFLF VPITTRWTLP RMRMDQLLNL GWKFLLPIAL GNLLLTTSSQ LLSF

References

[1]

"Phylogenetic and evolutionary implications of complete chloroplast genome sequences of four early-diverging angiosperms: Buxus (Buxaceae), Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium (Schisandraceae)." Hansen D.R., Dastidar S.G., Cai Z., Penaflor C., Kuehl J.V., Boore J.L., Jansen R.K. Mol. Phylogenet. Evol. 45:547-563(2007) [PubMed: 17644003] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	EF380354 Genomic DNA. Translation: ABQ52575.1.
RefSeq	YP_001294326.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5236710.
Family and domain databases
HAMAP	MF_01350. [Tree]
InterPro	IPR001694. NADH_UbQ_OxRdtase_su1. IPR018086. NADH_UbQ_OxRdtase_su1_CS. [Graphical view]
PANTHER	PTHR11432. Resp_NADH_DH_1. 1 hit.
Pfam	PF00146. NADHdh. 1 hit. [Graphical view]
PROSITE	PS00667. COMPLEX1_ND1_1. 1 hit. PS00668. COMPLEX1_ND1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NU1C_ILLOL

Accession

Primary (citable) accession number: A6MN00

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 21, 2007
Last sequence update:	July 24, 2007
Last modified:	June 16, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)