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A6LXU8

- ALF1_CLOB8

UniProt

A6LXU8 - ALF1_CLOB8

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Protein
Fructose-bisphosphate aldolase class 1
Gene
fda, Cbei_3039
Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei176 – 1761Proton acceptor By similarity
Active sitei213 – 2131Schiff-base intermediate with dihydroxyacetone-P By similarity

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

BioCyciCBEI290402:GHL5-3133-MONOMER.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolase
Gene namesi
Name:fda
Ordered Locus Names:Cbei_3039
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000565: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 295295Fructose-bisphosphate aldolase class 1UniRule annotation
PRO_1000083323Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290402.Cbei_3039.

Structurei

3D structure databases

ProteinModelPortaliA6LXU8.
SMRiA6LXU8. Positions 1-295.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3588.
HOGENOMiHOG000073502.
KOiK01623.
OMAiYTGDYLA.
OrthoDBiEOG6M6JJT.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6LXU8-1 [UniParc]FASTAAdd to Basket

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MNENQMKRIH TGKGFIAALD QSGGSTPKAL LEYGIKENSY SNEDEMFGLV    50
HEMRKRIIKS PAFTLEYILG AILFEDTMYR TIDNQYTPDY LWKEKNIVPF 100
LKVDKGLTEI ENGVQLMKPI SNLDDLLKHA VEKNIFGTKM RSVIKEANAK 150
GIKMLVNQQF EIGKQIVEAG LVPIIEPEVD IHSTDKEESE KLLKLEILEQ 200
LSKLDKETKV MLKLSIPTQD NFYIDLIDDP HVVRVVALSG GYSQAEAKER 250
LGRNHGLIAS FSRALSQGLT AQQTEEEFNG TISKSIKEIY EASIK 295
Length:295
Mass (Da):33,349
Last modified:July 24, 2007 - v1
Checksum:i5576E1369D51F0EE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR35178.1.
RefSeqiWP_012059231.1. NC_009617.1.
YP_001310134.1. NC_009617.1.

Genome annotation databases

EnsemblBacteriaiABR35178; ABR35178; Cbei_3039.
GeneIDi5294224.
KEGGicbe:Cbei_3039.
PATRICi19350262. VBICloBei69853_3154.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR35178.1 .
RefSeqi WP_012059231.1. NC_009617.1.
YP_001310134.1. NC_009617.1.

3D structure databases

ProteinModelPortali A6LXU8.
SMRi A6LXU8. Positions 1-295.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290402.Cbei_3039.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR35178 ; ABR35178 ; Cbei_3039 .
GeneIDi 5294224.
KEGGi cbe:Cbei_3039.
PATRICi 19350262. VBICloBei69853_3154.

Phylogenomic databases

eggNOGi COG3588.
HOGENOMi HOG000073502.
KOi K01623.
OMAi YTGDYLA.
OrthoDBi EOG6M6JJT.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
BioCyci CBEI290402:GHL5-3133-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51743 / NCIMB 8052.

Entry informationi

Entry nameiALF1_CLOB8
AccessioniPrimary (citable) accession number: A6LXU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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