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A6LXU8 (ALF1_CLOB8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-bisphosphate aldolase class 1
EC=4.1.2.13
Alternative name(s):
Fructose-biphosphate aldolase class I
Short name=FBP aldolase
Gene names
Name:fda
Ordered Locus Names:Cbei_3039
OrganismClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]
Taxonomic identifier290402 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length295 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP MF_00729

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP MF_00729

Sequence similarities

Belongs to the class I fructose-bisphosphate aldolase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionfructose-bisphosphate aldolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 295295Fructose-bisphosphate aldolase class 1 HAMAP MF_00729
PRO_1000083323

Sites

Active site1761Proton acceptor By similarity
Active site2131Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

Sequence LengthMass (Da)Tools
A6LXU8 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 5576E1369D51F0EE

FASTA29533,349
        10         20         30         40         50         60 
MNENQMKRIH TGKGFIAALD QSGGSTPKAL LEYGIKENSY SNEDEMFGLV HEMRKRIIKS 

        70         80         90        100        110        120 
PAFTLEYILG AILFEDTMYR TIDNQYTPDY LWKEKNIVPF LKVDKGLTEI ENGVQLMKPI 

       130        140        150        160        170        180 
SNLDDLLKHA VEKNIFGTKM RSVIKEANAK GIKMLVNQQF EIGKQIVEAG LVPIIEPEVD 

       190        200        210        220        230        240 
IHSTDKEESE KLLKLEILEQ LSKLDKETKV MLKLSIPTQD NFYIDLIDDP HVVRVVALSG 

       250        260        270        280        290 
GYSQAEAKER LGRNHGLIAS FSRALSQGLT AQQTEEEFNG TISKSIKEIY EASIK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000721 Genomic DNA. Translation: ABR35178.1.
RefSeqYP_001310134.1. NC_009617.1.

3D structure databases

ProteinModelPortalA6LXU8.
SMRA6LXU8. Positions 1-295.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6LXU8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5294224.
GenomeReviewsGene locus Cbei_3039 in contig CP000721_GR.
KEGGcbe:Cbei_3039.
PATRIC19350262. VBICloBei69853_3154.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3588.
HOGENOMHBG307137.
OMAGTKMRSV.
ProtClustDBPRK05377.

Enzyme and pathway databases

BioCycCBEI290402:CBEI_3039-MONOMER.

Family and domain databases

HAMAPMF_00729. FBP_aldolase_1.
[Tree]
InterProIPR000741. Aldolase_I.
IPR013785. Aldolase_TIM.
IPR023014. FBP_aldolase_I_bac.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01623.
PfamPF00274. Glycolytic. 1 hit.
[Graphical view]
PROSITEPS00158. ALDOLASE_CLASS_I. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALF1_CLOB8
AccessionPrimary (citable) accession number: A6LXU8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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