Reviewed, UniProtKB/Swiss-Prot A6LW95 (F16C1_CLOB8)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 3 1
      Short name=FBPase class 3 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 1

Gene names

Name:	fbp1
Ordered Locus Names:	Cbei_2467

Organism

Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]

Taxonomic identifier

290402 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	663 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01854
Cofactor	Manganese By similarity. HAMAP MF_01854
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01854
Sequence similarities	Belongs to the FBPase class 3 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: InterPro
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 663	663	Fructose-1,6-bisphosphatase class 3 1 HAMAP MF_01854		PRO_0000363078

Sequences

	Sequence		Length	Mass (Da)
	A6LW95-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 187BA8EB9A8D18F3	FASTA	663	76,856
	10 20 30 40 50 60 MKKYDLSTNE ISDNLRYLEL LSKQYPTINE ASTEIINLQA ILNLPKGTEH FLTDIHGEYE 70 80 90 100 110 120 PFIHVLKNAS GVIKRKIEDL FGNSLMQSEK KSLATLIYYP EQKLEIVLKQ EENIDDWYKI 130 140 150 160 170 180 NLYRLIEICR YVSSKYTRSK VRKALPKDFT YIIEELLHEQ PKGIDKYEYY EQIIRTIIDT 190 200 210 220 230 240 DRSKEFIVAL SKLIQRLVID RLHILGDIFD RGPGADIIMD TLVEYHSVDI QWGNHDILWM 250 260 270 280 290 300 GAACGSDVCI ANVIKNSLKY ANLDTLENGY GINLLPLATF SMDFYKDHPC NIFLPKMDCD 310 320 330 340 350 360 KKYSINEINL IAQMHKAIAI ILFKLEGQVI LRHPEFNMNH RLLLNKINYA EGTINLNGKT 370 380 390 400 410 420 HKLKDSFFPT IDPKNPYELT YDEKELIDKL KTSFINSDKY NKHVRFLYSN GSLYLKFNSN 430 440 450 460 470 480 LLYHGFIPLN EDGSFKKVKI ADKEYKGKEL LDKLDMLARE AYFSKDKDDS DNKKDIMWYL 490 500 510 520 530 540 WCGASSPLFG KDRMTIFEQY FIEEKETHYE KKDPYFSLRD NEDICKKILK EFGLSSPESH 550 560 570 580 590 600 IINGHMPVEE KNGESPIKAN GTLLVIDGGF SKAYQPKTGL AGYTLIYNSF GLQLVSHQPF 610 620 630 640 650 660 ESTEAAIKEE TDILSTTLLL EQVVNRKRVE DTDVGVTLKQ QIDDLKMLLN AYRKGLIKQQ NKI

References

[1]

"Complete sequence of Clostridium beijerinckii NCIMB 8052." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G., Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W., Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B., Blaschek H., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000721 Genomic DNA. Translation: ABR34625.1.
RefSeq	YP_001309581.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6LW95.
Genome annotation databases
GeneID	5293670.
GenomeReviews	Gene locus Cbei_2467 in contig CP000721_GR.
KEGG	cbe:Cbei_2467.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3855.
HOGENOM	HBG305683.
OMA	ISETIQR.
Family and domain databases
HAMAP	MF_01854. FBPase_class3. [Tree]
InterPro	IPR009164. FBPtase_Bacill. [Graphical view]
Pfam	PF06874. FBPase_2. 1 hit. [Graphical view]
PIRSF	PIRSF000906. FBPtase_Bacill. 1 hit.
ProtoNet	Search...

Entry information

Entry name

F16C1_CLOB8

Accession

Primary (citable) accession number: A6LW95

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	July 24, 2007
Last modified:	January 19, 2010
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)