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A6LU95

- TRPF_CLOB8

UniProt

A6LU95 - TRPF_CLOB8

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, Cbei_1753
Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCBEI290402:GHL5-1829-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:Cbei_1753
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000565: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_1000197093Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290402.Cbei_1753.

Structurei

3D structure databases

ProteinModelPortaliA6LU95.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LU95-1 [UniParc]FASTAAdd to Basket

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MIQVKICGIT NKNEIKYLNI LKPEYMGFVF TKSKRQVTVR EAKQLSNNLD    50
KQIKIVGVFK DNSIDEILDV INILPLNIIQ LHGKEDENFI SSLKARVEKS 100
VSIWKALSIS DAENIRKYAD HKYRDSIDNI LIDGDKPGSG ETFPLEDICE 150
LLKVDSNKEN NCNLTNNTCS FFLAGGITPE NVAERIVKVS PYGIDVSSGI 200
EITNEDGTRT KSFEKMRSLI EKVRAININ 229
Length:229
Mass (Da):25,826
Last modified:July 24, 2007 - v1
Checksum:i75D4C26EB115DBA5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR33925.1.
RefSeqiYP_001308881.1. NC_009617.1.

Genome annotation databases

EnsemblBacteriaiABR33925; ABR33925; Cbei_1753.
GeneIDi5292969.
KEGGicbe:Cbei_1753.
PATRICi19347536. VBICloBei69853_1810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR33925.1 .
RefSeqi YP_001308881.1. NC_009617.1.

3D structure databases

ProteinModelPortali A6LU95.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290402.Cbei_1753.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR33925 ; ABR33925 ; Cbei_1753 .
GeneIDi 5292969.
KEGGi cbe:Cbei_1753.
PATRICi 19347536. VBICloBei69853_1810.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CBEI290402:GHL5-1829-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51743 / NCIMB 8052.

Entry informationi

Entry nameiTRPF_CLOB8
AccessioniPrimary (citable) accession number: A6LU95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 24, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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