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A6LU95

- TRPF_CLOB8

UniProt

A6LU95 - TRPF_CLOB8

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciCBEI290402:GHL5-1829-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:Cbei_1753
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000565: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197093Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290402.Cbei_1753.

Structurei

3D structure databases

ProteinModelPortaliA6LU95.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPDYAGFV.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LU95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIQVKICGIT NKNEIKYLNI LKPEYMGFVF TKSKRQVTVR EAKQLSNNLD
60 70 80 90 100
KQIKIVGVFK DNSIDEILDV INILPLNIIQ LHGKEDENFI SSLKARVEKS
110 120 130 140 150
VSIWKALSIS DAENIRKYAD HKYRDSIDNI LIDGDKPGSG ETFPLEDICE
160 170 180 190 200
LLKVDSNKEN NCNLTNNTCS FFLAGGITPE NVAERIVKVS PYGIDVSSGI
210 220
EITNEDGTRT KSFEKMRSLI EKVRAININ
Length:229
Mass (Da):25,826
Last modified:July 24, 2007 - v1
Checksum:i75D4C26EB115DBA5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR33925.1.
RefSeqiYP_001308881.1. NC_009617.1.

Genome annotation databases

EnsemblBacteriaiABR33925; ABR33925; Cbei_1753.
GeneIDi5292969.
KEGGicbe:Cbei_1753.
PATRICi19347536. VBICloBei69853_1810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR33925.1 .
RefSeqi YP_001308881.1. NC_009617.1.

3D structure databases

ProteinModelPortali A6LU95.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290402.Cbei_1753.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR33925 ; ABR33925 ; Cbei_1753 .
GeneIDi 5292969.
KEGGi cbe:Cbei_1753.
PATRICi 19347536. VBICloBei69853_1810.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PDYAGFV.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci CBEI290402:GHL5-1829-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51743 / NCIMB 8052.

Entry informationi

Entry nameiTRPF_CLOB8
AccessioniPrimary (citable) accession number: A6LU95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: July 24, 2007
Last modified: October 1, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3