A6LT24 (A6LT24_CLOB8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphoribosyl-ATP pyrophosphatase HAMAP MF_01020
Short name=PRA-PH HAMAP MF_01020
EC=3.6.1.31 HAMAP MF_01020

Gene names

Name:	hisE HAMAP MF_01020
Ordered Locus Names:	Cbei_1324

Organism

Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP] EMBL ABR33504.1

Taxonomic identifier

290402 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	108 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. HAMAP MF_01020
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9. HAMAP MF_01020
Subcellular location	Cytoplasm By similarity HAMAP MF_01020.
Sequence similarities	Belongs to the PRA-PH family. HAMAP MF_01020

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01020
Cellular component	Cytoplasm HAMAP MF_01020
Ligand	ATP-binding HAMAP MF_01020 Nucleotide-binding
Molecular function	Hydrolase HAMAP MF_01020 EMBL ABR33504.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosyl-ATP diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6LT24 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 2BC14804A2113527	FASTA	108	12,556
	10 20 30 40 50 60 MDENIKALYE TILKRKTEGE EGSYTKYLFE KGTNKILKKV GEECTEVIIS CKENNKEEQI 70 80 90 100 NEICDLTYHL LVLMAQMNIS IEEVGAELEK RRNKINNFKG ERKPITNV

References

[1]

"Complete sequence of Clostridium beijerinckii NCIMB 8052." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G., Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W., Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B., Blaschek H., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51743 / NCIMB 8052.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000721 Genomic DNA. Translation: ABR33504.1.
RefSeq	YP_001308460.1. NC_009617.1.
3D structure databases
ProteinModelPortal	A6LT24.
SMR	A6LT24. Positions 5-95.
ModBase	Search...
Protein-protein interaction databases
STRING	A6LT24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5292548.
GenomeReviews	Gene locus Cbei_1324 in contig CP000721_GR.
KEGG	cbe:Cbei_1324.
PATRIC	19346628. VBICloBei69853_1360.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0140.
HOGENOM	HBG646527.
OMA	EMRRREN.
ProtClustDB	CLSK2327033.
Family and domain databases
HAMAP	MF_01020. HisE. [Tree]
InterPro	IPR008179. PRib-ATP_PPHydrolase. IPR021130. PRib-ATP_PPHydrolase-like. [Graphical view]
KO	K01523.
Pfam	PF01503. PRA-PH. 1 hit. [Graphical view]
TIGRFAMs	TIGR03188. Histidine_hisI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6LT24_CLOB8

Accession

Primary (citable) accession number: A6LT24

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)