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Reviewed, UniProtKB/Swiss-Prot A6LSL7 (ACKA_CLOB8)

Last modified June 16, 2009. Version 14. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase
Gene names
Name: ackA
Ordered Locus Names: Cbei_1165
OrganismClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]
Taxonomic identifier290402 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

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Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetokinase family.

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Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

phosphorylation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Acetate kinase HAMAP MF_00020
PRO_1000074183

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Sequences

Sequence LengthMass (Da)Tools
A6LSL7-1 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 531D97D40AF3D507

FASTA40043,574
        10         20         30         40         50         60 
MKVLVINCGS SSLKYQLIDM SNEESLAQGL VERIGITGSI LTQKVEGKDK YVVETPLKDH 

        70         80         90        100        110        120 
QDAIELVLKC LVDENHGVIS SMDEISAVGH RVVHGGEKYA TSVVINEEVI KALDEFTKLA 

       130        140        150        160        170        180 
PLHNPPNIIG INACKALMPK TPMVAVFDTA FHQTMPEKAF MYALPYELYT EDHVRRYGFH 

       190        200        210        220        230        240 
GTSHKYVAGE MAKLMNKDIS DLKIVTCHIG NGVSITAVDG GKSVDTTMGF TPLDGIIMGS 

       250        260        270        280        290        300 
RSGSIDPAIV TYLVKEKGYS IDEVNDILNK KSGVLGISGI GTDFRDIRSA VENDNDPRAL 

       310        320        330        340        350        360 
LTMDIFGYQV KKQIGAYAAV MGGVDAIVFT AGIGEHAPEI RSRALTNMEF LGIEVDLEKN 

       370        380        390        400 
ESHNIGDGME ISKETSKVKV VVIPTNEELM IAKETLELVK

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References

[1]"Complete sequence of Clostridium beijerinckii NCIMB 8052."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G., Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W., Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B., Blaschek H., Richardson P.
Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000721 Genomic DNA. Translation: ABR33347.1.
RefSeqYP_001308303.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5292391.
GenomeReviewsGene locus Cbei_1165 in contig CP000721_GR.
KEGGcbe:Cbei_1165.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA6LSL7. CFDTSWH.

Family and domain databases

HAMAPMF_00020.
[Tree]
InterProIPR000890. Acetate_kin.
IPR004372. AckA.
[Graphical view]
PANTHERPTHR21060. Acetate_kin. 1 hit.
PTHR21060:SF11. AckA. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. ackA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameACKA_CLOB8
AccessionPrimary (citable) accession number: A6LSL7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: June 16, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents