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A6LSL7 (ACKA_CLOB8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:Cbei_1165
OrganismClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]
Taxonomic identifier290402 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Acetate kinase HAMAP MF_00020
PRO_1000074183

Sequences

Sequence LengthMass (Da)Tools
A6LSL7 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 531D97D40AF3D507

FASTA40043,574
        10         20         30         40         50         60 
MKVLVINCGS SSLKYQLIDM SNEESLAQGL VERIGITGSI LTQKVEGKDK YVVETPLKDH 

        70         80         90        100        110        120 
QDAIELVLKC LVDENHGVIS SMDEISAVGH RVVHGGEKYA TSVVINEEVI KALDEFTKLA 

       130        140        150        160        170        180 
PLHNPPNIIG INACKALMPK TPMVAVFDTA FHQTMPEKAF MYALPYELYT EDHVRRYGFH 

       190        200        210        220        230        240 
GTSHKYVAGE MAKLMNKDIS DLKIVTCHIG NGVSITAVDG GKSVDTTMGF TPLDGIIMGS 

       250        260        270        280        290        300 
RSGSIDPAIV TYLVKEKGYS IDEVNDILNK KSGVLGISGI GTDFRDIRSA VENDNDPRAL 

       310        320        330        340        350        360 
LTMDIFGYQV KKQIGAYAAV MGGVDAIVFT AGIGEHAPEI RSRALTNMEF LGIEVDLEKN 

       370        380        390        400 
ESHNIGDGME ISKETSKVKV VVIPTNEELM IAKETLELVK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000721 Genomic DNA. Translation: ABR33347.1.
RefSeqYP_001308303.1. NC_009617.1.

3D structure databases

ProteinModelPortalA6LSL7.
SMRA6LSL7. Positions 1-400.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6LSL7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5292391.
GenomeReviewsGene locus Cbei_1165 in contig CP000721_GR.
KEGGcbe:Cbei_1165.
PATRIC19346298. VBICloBei69853_1195.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMAERNNIRA.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycCBEI290402:CBEI_1165-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_CLOB8
AccessionPrimary (citable) accession number: A6LSL7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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