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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei139GTPUniRule annotation1
Binding sitei143GTPUniRule annotation1
Binding sitei187GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 25GTPUniRule annotation5
Nucleotide bindingi108 – 110GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Cbei_1118Imported
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)Imported
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000565 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi290402.Cbei_1118

Structurei

3D structure databases

ProteinModelPortaliA6LSH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 205TubulinInterPro annotationAdd BLAST193
Domaini207 – 324Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A6LSH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDFETDMQE LTNIKVIGCG GGGSNAVNRM IVEGLKNVEF IAINTDKQAL
60 70 80 90 100
MLSNADQKIQ IGEKLTKGLG AGANPEIGKK AAEESREEIT ASIKGANMVF
110 120 130 140 150
ITAGMGGGTG TGAAPIVAEI AKSMEILTVG VVTKPFPFEG KRRMRHAEMG
160 170 180 190 200
IATLKEKVDT LVIIPNERLL NMADKKTTLL DSFKLADEVL RQGVQAISDL
210 220 230 240 250
ITITGVINAD FADIKAVMLN KGLAHMGVGF GKGDTRTQDA VKQAISSPLL
260 270 280 290 300
ETSIDGATDV IINFTGGADL GALEVYDAAD VVREAVDPDA NIIVGAVIDE
310 320 330 340 350
TLNEEIRITV IATGFESENN RLSLGSIVEE SKKVQPQVKE VAKEQQEVAV
360 370
DAKEPEMTSN NYEPDDLDIP VFLRRQKRH
Length:379
Mass (Da):40,590
Last modified:July 24, 2007 - v1
Checksum:i84F21B2E3E6EB0B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000721 Genomic DNA Translation: ABR33300.1
RefSeqiWP_011968458.1, NC_009617.1

Genome annotation databases

EnsemblBacteriaiABR33300; ABR33300; Cbei_1118
KEGGicbe:Cbei_1118

Similar proteinsi

Entry informationi

Entry nameiA6LSH0_CLOB8
AccessioniPrimary (citable) accession number: A6LSH0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health