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A6LR05

- PGK_CLOB8

UniProt

A6LR05 - PGK_CLOB8

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (24 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei38 – 381SubstrateUniRule annotation
    Binding sitei117 – 1171SubstrateUniRule annotation
    Binding sitei150 – 1501SubstrateUniRule annotation
    Binding sitei201 – 2011ATPUniRule annotation
    Binding sitei291 – 2911ATP; via carbonyl oxygenUniRule annotation
    Binding sitei322 – 3221ATPUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi348 – 3514ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCBEI290402:GHL5-663-MONOMER.
    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
    Gene namesi
    Name:pgkUniRule annotation
    Ordered Locus Names:Cbei_0598
    OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
    Taxonomic identifieri290402 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000000565: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 391391Phosphoglycerate kinasePRO_1000076584Add
    BLAST

    Proteomic databases

    PRIDEiA6LR05.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi290402.Cbei_0598.

    Structurei

    3D structure databases

    ProteinModelPortaliA6LR05.
    SMRiA6LR05. Positions 4-391.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni23 – 253Substrate bindingUniRule annotation
    Regioni61 – 644Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0126.
    HOGENOMiHOG000227108.
    KOiK00927.
    OMAiWEALDIG.
    OrthoDBiEOG64N9Z0.

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A6LR05-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNFNKKTIED IEVSGKKVLV RCDFNVPLKD GVITDENRLV GALPTIKYLV    50
    EKGAKVILCS HLGKDASKSL APVATRLSEM LGKEVVFARD EEVVGENAKK 100
    AVSEMKDGDI VLLENTRCRK EETKNIPEFS KELASLADVF VNDAFGTAHR 150
    AHCSTVGVTD YLDTAVCGYL IQKELKFLGN AVESPVRPFV AILGGAKVSD 200
    KIAVINNLLD KVNTIIIGGG MAYTFLKAQG YEIGTSLVEE DRLEYAKEMV 250
    AKAAEKGVKF LLPVDHRVAA EFKDVEATIT EDQNIPVGNM GLDIGPKTET 300
    LYADAIKDAK TVIWNGPMGV FEFENYNKGT IAVAKAMADA DATTIIGGGD 350
    SAAAVNILGF GDKMTHISTG GGASLEFLEG KVLPGIAALN D 391
    Length:391
    Mass (Da):41,877
    Last modified:July 24, 2007 - v1
    Checksum:i9061088C6A5B02A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000721 Genomic DNA. Translation: ABR32785.1.
    RefSeqiYP_001307741.1. NC_009617.1.

    Genome annotation databases

    EnsemblBacteriaiABR32785; ABR32785; Cbei_0598.
    GeneIDi5291829.
    KEGGicbe:Cbei_0598.
    PATRICi19345126. VBICloBei69853_0614.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000721 Genomic DNA. Translation: ABR32785.1 .
    RefSeqi YP_001307741.1. NC_009617.1.

    3D structure databases

    ProteinModelPortali A6LR05.
    SMRi A6LR05. Positions 4-391.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290402.Cbei_0598.

    Proteomic databases

    PRIDEi A6LR05.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR32785 ; ABR32785 ; Cbei_0598 .
    GeneIDi 5291829.
    KEGGi cbe:Cbei_0598.
    PATRICi 19345126. VBICloBei69853_0614.

    Phylogenomic databases

    eggNOGi COG0126.
    HOGENOMi HOG000227108.
    KOi K00927.
    OMAi WEALDIG.
    OrthoDBi EOG64N9Z0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .
    BioCyci CBEI290402:GHL5-663-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51743 / NCIMB 8052.

    Entry informationi

    Entry nameiPGK_CLOB8
    AccessioniPrimary (citable) accession number: A6LR05
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3