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A6LR05

- PGK_CLOB8

UniProt

A6LR05 - PGK_CLOB8

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381SubstrateUniRule annotation
Binding sitei117 – 1171SubstrateUniRule annotation
Binding sitei150 – 1501SubstrateUniRule annotation
Binding sitei201 – 2011ATPUniRule annotation
Binding sitei291 – 2911ATP; via carbonyl oxygenUniRule annotation
Binding sitei322 – 3221ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi348 – 3514ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCBEI290402:GHL5-663-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:Cbei_0598
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000565: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Phosphoglycerate kinasePRO_1000076584Add
BLAST

Proteomic databases

PRIDEiA6LR05.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi290402.Cbei_0598.

Structurei

3D structure databases

ProteinModelPortaliA6LR05.
SMRiA6LR05. Positions 4-391.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni23 – 253Substrate bindingUniRule annotation
Regioni61 – 644Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6LR05-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNFNKKTIED IEVSGKKVLV RCDFNVPLKD GVITDENRLV GALPTIKYLV
60 70 80 90 100
EKGAKVILCS HLGKDASKSL APVATRLSEM LGKEVVFARD EEVVGENAKK
110 120 130 140 150
AVSEMKDGDI VLLENTRCRK EETKNIPEFS KELASLADVF VNDAFGTAHR
160 170 180 190 200
AHCSTVGVTD YLDTAVCGYL IQKELKFLGN AVESPVRPFV AILGGAKVSD
210 220 230 240 250
KIAVINNLLD KVNTIIIGGG MAYTFLKAQG YEIGTSLVEE DRLEYAKEMV
260 270 280 290 300
AKAAEKGVKF LLPVDHRVAA EFKDVEATIT EDQNIPVGNM GLDIGPKTET
310 320 330 340 350
LYADAIKDAK TVIWNGPMGV FEFENYNKGT IAVAKAMADA DATTIIGGGD
360 370 380 390
SAAAVNILGF GDKMTHISTG GGASLEFLEG KVLPGIAALN D
Length:391
Mass (Da):41,877
Last modified:July 24, 2007 - v1
Checksum:i9061088C6A5B02A8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR32785.1.
RefSeqiYP_001307741.1. NC_009617.1.

Genome annotation databases

EnsemblBacteriaiABR32785; ABR32785; Cbei_0598.
GeneIDi5291829.
KEGGicbe:Cbei_0598.
PATRICi19345126. VBICloBei69853_0614.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000721 Genomic DNA. Translation: ABR32785.1 .
RefSeqi YP_001307741.1. NC_009617.1.

3D structure databases

ProteinModelPortali A6LR05.
SMRi A6LR05. Positions 4-391.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290402.Cbei_0598.

Proteomic databases

PRIDEi A6LR05.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR32785 ; ABR32785 ; Cbei_0598 .
GeneIDi 5291829.
KEGGi cbe:Cbei_0598.
PATRICi 19345126. VBICloBei69853_0614.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci CBEI290402:GHL5-663-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51743 / NCIMB 8052.

Entry informationi

Entry nameiPGK_CLOB8
AccessioniPrimary (citable) accession number: A6LR05
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3