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A6LQ99

- G6PI_CLOB8

UniProt

A6LQ99 - G6PI_CLOB8

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei291 – 2911Proton donorUniRule annotation
Active sitei312 – 3121UniRule annotation
Active sitei426 – 4261UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCBEI290402:GHL5-374-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Cbei_0341
OrganismiClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Taxonomic identifieri290402 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000000565: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Glucose-6-phosphate isomerasePRO_1000081234Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290402.Cbei_0341.

Structurei

3D structure databases

ProteinModelPortaliA6LQ99.
SMRiA6LQ99. Positions 4-449.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiAIAFREF.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6LQ99-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKGISLDLS KVSPYLEEAE LENMESMVKA VHEDLHNKTG AGNDFLGWVD
60 70 80 90 100
LPVNYDKEEF ARIKKAAEKI KSDSDVLIVI GIGGSYLGAR AAIEMLTNNF
110 120 130 140 150
HNVLGSDKRK VPQIFFAGNN ISSTYMAELL QVIEGKDVSL NVISKSGTTT
160 170 180 190 200
EPAIAFRILK SYLEKKYGVE EARKRIYATT DKARGALKTL ADSEGYETFV
210 220 230 240 250
VPDDVGGRFT VLTAVGLLPI AAAGIDIDEM MKGAADARTA YSVPSIKEND
260 270 280 290 300
AYKYAAARNA LYNKGASIEV LVNYEPSLHY FNEWWKQLYG ESEGKDHKGL
310 320 330 340 350
FPAAVDFSTD LHSMGQYIQD GRRIMFETVV NIEKPKYEIN IEEADNDLDG
360 370 380 390 400
LNFLAGKTMD FVNKKAFEGT LLAHNDGGVP NMILNVPEIS AYYFGYMVYF
410 420 430 440
FEKACGISGY LLAINPFNQP GVEAYKKNMF ALLGKPGYED MKAELEKRL
Length:449
Mass (Da):49,804
Last modified:July 24, 2007 - v1
Checksum:iAF62955117222423
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000721 Genomic DNA. Translation: ABR32529.1.
RefSeqiWP_011967690.1. NC_009617.1.
YP_001307485.1. NC_009617.1.

Genome annotation databases

EnsemblBacteriaiABR32529; ABR32529; Cbei_0341.
GeneIDi5291573.
KEGGicbe:Cbei_0341.
PATRICi19344536. VBICloBei69853_0351.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000721 Genomic DNA. Translation: ABR32529.1 .
RefSeqi WP_011967690.1. NC_009617.1.
YP_001307485.1. NC_009617.1.

3D structure databases

ProteinModelPortali A6LQ99.
SMRi A6LQ99. Positions 4-449.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290402.Cbei_0341.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR32529 ; ABR32529 ; Cbei_0341 .
GeneIDi 5291573.
KEGGi cbe:Cbei_0341.
PATRICi 19344536. VBICloBei69853_0351.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi AIAFREF.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CBEI290402:GHL5-374-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51743 / NCIMB 8052.

Entry informationi

Entry nameiG6PI_CLOB8
AccessioniPrimary (citable) accession number: A6LQ99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: November 26, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3