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A6LPP6 (EFTU_CLOB8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Elongation factor Tu
Short name=EF-Tu
Gene names
Name:tuf1
Ordered Locus Names:Cbei_0136
AND
Name:tuf2
Ordered Locus Names:Cbei_0149
OrganismClostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]
Taxonomic identifier290402 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium ›

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processGTP catabolic process

Inferred from electronic annotation. Source: GOC

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000337355

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding81 – 855GTP By similarity
Nucleotide binding136 – 1394GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
A6LPP6 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 92C3CC2CC5BB941C

FASTA39743,624
        10         20         30         40         50         60 
MAKAKYERSK PHVNIGTIGH VDHGKTTLTA AITTVLANKG FAEAFNYADI DKAPEEKERG 

        70         80         90        100        110        120 
ITINTAHVEY QTENRHYAHV DCPGHADYVK NMITGAAQMD GAILVVSAAD GPMPQTREHI 

       130        140        150        160        170        180 
LLGSRVGIQY IVVFLNKADM VDDPELLELV EMEVRELLSE YDFPGDDIPV ITGSALKALE 

       190        200        210        220        230        240 
NPTDEEAIKP IMDLMEAVDS YIPTPERATD KPFLMPIEDV FTITGRGTVA TGRVEAGVLH 

       250        260        270        280        290        300 
VGDEVEIVGL TEEKKKVVVT GIEMFRKLLD EAQAGDNIGA LLRGVQRTDI ERGQVLSKPN 

       310        320        330        340        350        360 
SVHPHTKFVG QVYVLKKEEG GRHTPFFDGY RPQFYFRTTD VTGSIKLPDG MEMVMPGDHI 

       370        380        390 
DMNVELITPI AMDEGLRFAI REGGRTVGSG VVTKIVE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000721 Genomic DNA. Translation: ABR32326.1.
CP000721 Genomic DNA. Translation: ABR32339.1.
RefSeqYP_001307282.1. NC_009617.1.
YP_001307295.1. NC_009617.1.

3D structure databases

ProteinModelPortalA6LPP6.
SMRA6LPP6. Positions 2-397.
ModBaseSearch...

Protein-protein interaction databases

STRING290402.Cbei_0149.

Proteomic databases

PRIDEA6LPP6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR32326; ABR32326; Cbei_0136.
ABR32339; ABR32339; Cbei_0149.
GeneID5291383.
5296287.
KEGGcbe:Cbei_0136.
cbe:Cbei_0149.
PATRIC19344112. VBICloBei69853_0141.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMACEFVGYN.
ProtClustDBPRK00049.

Enzyme and pathway databases

BioCycCBEI290402:GHL5-277-MONOMER.
CBEI290402:GHL5-290-MONOMER.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR005225. Small_GTP-bd_dom.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
IPR009000. Transl_elong_init/rib_B-barrel.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50465. Elong_init_C. 1 hit.
SSF50447. Translat_factor. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_CLOB8
AccessionPrimary (citable) accession number: A6LPP6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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