Reviewed, UniProtKB/Swiss-Prot A6LPF0 (COMB_CLOB8)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Cbei_0040

Organism

Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum) [Complete proteome] [HAMAP]

Taxonomic identifier

290402 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000081392

Sequences

	Sequence		Length	Mass (Da)
	A6LPF0-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 56BD70DDCCFFB185	FASTA	238	26,690
	10 20 30 40 50 60 MKIDIIISAD DIVESRVRNK IAVIIDIFRA TSVIITALDN GAREVIPYLT IEETLEYAKK 70 80 90 100 110 120 LSRDNYILGG ERKAVKIEGF DLSNSPLEYI KEKVEDKTVL MTTTNGTRAL TKSMEAKRVF 130 140 150 160 170 180 IGAMINGESV AKKLININDD VVIINAGTNG NFSMDDFICS GYIINRILDV NRNIELTDIA 190 200 210 220 230 KTACMIYKEN INILSYVREA SHYSVMKSLG LNNDIDYCIK KSIIDIVPEY KDGKITCE

References

[1]

"Complete sequence of Clostridium beijerinckii NCIMB 8052." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Tapia R., Brainard J., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Mikhailova N., Bennet G., Cann I., Chen J.-S., Contreras A.L., Jones D., Kashket E., Mitchell W., Stoddard S., Schwarz W., Qureshi N., Young M., Shi Z., Ezeji T., White B., Blaschek H., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000721 Genomic DNA. Translation: ABR32230.1.
RefSeq	YP_001307186.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5291274.
GenomeReviews	Gene locus Cbei_0040 in contig CP000721_GR.
KEGG	cbe:Cbei_0040.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A6LPF0. DFICSGY.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00298. 2-ph_phosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_CLOB8

Accession

Primary (citable) accession number: A6LPF0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	July 24, 2007
Last modified:	May 5, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)