A6LNG2 (TAL_THEM4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	Tmel_1619

Organism

Thermosipho melanesiensis (strain BI429 / DSM 12029) [Complete proteome] [HAMAP]

Taxonomic identifier

391009 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length	216 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 216	216	Probable transaldolase HAMAP MF_00494		PRO_1000060483
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6LNG2 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 6A3AEB6D0659CA5F	FASTA	216	23,859
	10 20 30 40 50 60 MKIFLDTAKI DEIKKGVEWG IVDGVTTNPT LVSKAGTPFK ETIKQICEIV QGPVSAEVVS 70 80 90 100 110 120 SDWQGMVEEA RNLAKIDEHV VIKIPMTPDG LKAVKILSTE GIKTNVTLVF SANQSLLAAK 130 140 150 160 170 180 AGASYVSPFV GRMDDIANDG MRMVEEIITI YSNYGFETEI IVASIRHPRH VLEAALMGAD 190 200 210 IATVPFAVLE KMFYHPMTDL GIERFLRDWE KYKAGR

References

[1]

"Complete sequence of Thermosipho melanesiensis BI429." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BI429 / DSM 12029.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000716 Genomic DNA. Translation: ABR31463.1.
RefSeq	YP_001306848.1. NC_009616.1.
3D structure databases
ProteinModelPortal	A6LNG2.
SMR	A6LNG2. Positions 1-212.
ModBase	Search...
Protein-protein interaction databases
STRING	A6LNG2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5297082.
GenomeReviews	Gene locus Tmel_1619 in contig CP000716_GR.
KEGG	tme:Tmel_1619.
NMPDR	fig|391009.4.peg.1670.
PATRIC	23924529. VBITheMel19269_1678.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0176.
HOGENOM	HBG533000.
OMA	KVNVTLC.
ProtClustDB	PRK01362.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_THEM4

Accession

Primary (citable) accession number: A6LNG2

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 24, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program