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A6LMV5 (APGM_THEM4) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1
Gene names
Name:apgM
Ordered Locus Names:Tmel_1409
OrganismThermosipho melanesiensis (strain BI429 / DSM 12029) [Complete proteome] [HAMAP]
Taxonomic identifier391009 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_B

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_B

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_B

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
   Biological processGlycolysis
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmetal ion binding

Inferred from electronic annotation. Source: InterPro

phosphoglycerate mutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 402402Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_B
PRO_1000068385

Sequences

Sequence LengthMass (Da)Tools
A6LMV5 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 9AA35C950778BD4B

FASTA40244,645
        10         20         30         40         50         60 
MIDRQQILNE LISPNSSKIV LLVMDGIGDI PGEDGLTPLQ KANTPKLDEL AKQSDLGQTI 

        70         80         90        100        110        120 
PVLPGITPGS GPGHLGIFGY DPLKYQIGRG ILEALGIDVE VGEKDLVARG NFATLEGDII 

       130        140        150        160        170        180 
VDRRAGRPSS EESAKVVEIL NENIHKIEDV EVKFYPGKEH RFVVKLTGEG LYDKLEDADP 

       190        200        210        220        230        240 
QKEGKPIKYT KALDESSKKS EKIINILIDR IKEVLKDQQK MNFALLRGFS KYPNLPSFGD 

       250        260        270        280        290        300 
VYKLRPAAIA VYPMYKGLAK LVGMEILKTG QTIEDEFKTV KENWEKYDFF YVHVKKTDSY 

       310        320        330        340        350        360 
GEDGNFESKV KVIEEVDKNL GLLLELKPDV LIVTGDHSTP CAMKGHSFHP VPLMIYSKFT 

       370        380        390        400 
RKGLSKLYNE FECARGTLGT IPAVDVMSLA LAYAGRLEKY GA

« Hide

References

[1]"Complete sequence of Thermosipho melanesiensis BI429."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BI429 / DSM 12029.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000716 Genomic DNA. Translation: ABR31256.1.
RefSeqYP_001306641.1. NC_009616.1.

3D structure databases

ProteinModelPortalA6LMV5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6LMV5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5298026.
GenomeReviewsGene locus Tmel_1409 in contig CP000716_GR.
KEGGtme:Tmel_1409.
NMPDRfig|391009.4.peg.1457.
PATRIC23924087. VBITheMel19269_1462.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3635.
HOGENOMHBG463247.
OMADIAFRCN.
ProtClustDBPRK04135.

Family and domain databases

HAMAPMF_01402_B. ApgM_B.
[Tree]
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR023665. ApgAM.
IPR004456. BisP-indep_Pglycerate_Mutase.
IPR006124. Metalloenzyme.
[Graphical view]
Gene3DG3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KOK15635.
PfamPF01676. Metalloenzyme. 1 hit.
PF10143. PhosphMutase. 1 hit.
[Graphical view]
PIRSFPIRSF006392. IPGAM_arch. 1 hit.
SUPFAMSSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMsTIGR00306. ApgM. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAPGM_THEM4
AccessionPrimary (citable) accession number: A6LMV5
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 24, 2007
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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