Reviewed, UniProtKB/Swiss-Prot A6LMV5 (APGM_THEM4)

Names and origin

Protein names

Recommended name:
    Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
      Short name=Phosphoglyceromutase
      Short name=BPG-independent PGAM
      Short name=aPGAM
    EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	Tmel_1409

Organism

Thermosipho melanesiensis (strain BI429 / DSM 12029) [Complete proteome] [HAMAP]

Taxonomic identifier

391009 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length	402 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity.
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 402	402	Probable 2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402		PRO_1000068385

Sequences

	Sequence		Length	Mass (Da)
	A6LMV5-1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 9AA35C950778BD4B	FASTA	402	44,645
	10 20 30 40 50 60 MIDRQQILNE LISPNSSKIV LLVMDGIGDI PGEDGLTPLQ KANTPKLDEL AKQSDLGQTI 70 80 90 100 110 120 PVLPGITPGS GPGHLGIFGY DPLKYQIGRG ILEALGIDVE VGEKDLVARG NFATLEGDII 130 140 150 160 170 180 VDRRAGRPSS EESAKVVEIL NENIHKIEDV EVKFYPGKEH RFVVKLTGEG LYDKLEDADP 190 200 210 220 230 240 QKEGKPIKYT KALDESSKKS EKIINILIDR IKEVLKDQQK MNFALLRGFS KYPNLPSFGD 250 260 270 280 290 300 VYKLRPAAIA VYPMYKGLAK LVGMEILKTG QTIEDEFKTV KENWEKYDFF YVHVKKTDSY 310 320 330 340 350 360 GEDGNFESKV KVIEEVDKNL GLLLELKPDV LIVTGDHSTP CAMKGHSFHP VPLMIYSKFT 370 380 390 400 RKGLSKLYNE FECARGTLGT IPAVDVMSLA LAYAGRLEKY GA

References

[1]

"Complete sequence of Thermosipho melanesiensis BI429." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P. Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000716 Genomic DNA. Translation: ABR31256.1.
RefSeq	YP_001306641.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A6LMV5.
Genome annotation databases
GeneID	5298026.
GenomeReviews	Gene locus Tmel_1409 in contig CP000716_GR.
KEGG	tme:Tmel_1409.
NMPDR	fig|391009.4.peg.1457.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	ITGDHST.
Family and domain databases
HAMAP	MF_01402. [Tree]
InterPro	IPR004456. APGAM_arc. IPR019304. bisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
ProDom	PD004704. APGAM_DeoB. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00306. apgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_THEM4

Accession

Primary (citable) accession number: A6LMV5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	July 24, 2007
Last modified:	November 3, 2009
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)