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A6LL97 (A6LL97_THEM4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase HAMAP MF_00163
Short name=PDF HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase HAMAP MF_00163
Gene names
Name:def HAMAP MF_00163
Ordered Locus Names:Tmel_0837
OrganismThermosipho melanesiensis (strain BI429 / DSM 12029) [Complete proteome] [HAMAP]
Taxonomic identifier391009 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermosipho

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1281 By similarity HAMAP MF_00163
Metal binding851Iron By similarity HAMAP MF_00163
Metal binding1271Iron By similarity HAMAP MF_00163
Metal binding1311Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A6LL97 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 89078C42EF78EE0F

FASTA16519,187
        10         20         30         40         50         60 
MRIRLYGDPI LRKSAKAVKD FKYLQEIKED MLKTMYLEDG VGLAAPQVGL SLRFFVMDDG 

        70         80         90        100        110        120 
SGPLFIVNPE IIAHSEEKEI GEEGCLSLPG IFENVERYKW VKLKFQDEYG KVQTRLFEGY 

       130        140        150        160 
SARIVQHERD HLDGILFIDH LPNAVKRRLA PELSKIMRMR MEEKK

« Hide

References

[1]"Complete sequence of Thermosipho melanesiensis BI429."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BI429 / DSM 12029.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000716 Genomic DNA. Translation: ABR30698.1.
RefSeqYP_001306083.1. NC_009616.1.

3D structure databases

ProteinModelPortalA6LL97.
SMRA6LL97. Positions 2-142.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6LL97.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5297994.
GenomeReviewsGene locus Tmel_0837 in contig CP000716_GR.
KEGGtme:Tmel_0837.
NMPDRfig|391009.4.peg.875.
PATRIC23922901. VBITheMel19269_0878.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAMINAHIE.
ProtClustDBPRK14597.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6LL97_THEM4
AccessionPrimary (citable) accession number: A6LL97
Entry history
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info