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Protein

Glycogen synthase

Gene

glgA

Organism
Thermosipho melanesiensis (strain BI429 / DSM 12029)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciTMEL391009:GHM1-82-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:Tmel_0077
OrganismiThermosipho melanesiensis (strain BI429 / DSM 12029)
Taxonomic identifieri391009 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermosipho
ProteomesiUP000001110: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 481481Glycogen synthasePRO_1000014389Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi391009.Tmel_0077.

Structurei

3D structure databases

ProteinModelPortaliA6LJ53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LJ53-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVALISYEV YPFAKVGGLA DVVGALPKYL EKASVKPIVI MPKHKVVEKN
60 70 80 90 100
ARNLDKVMEK ISIPYLKTDE TFDIYKTIVP KTNVPIYFVA NEYYFSAENV
110 120 130 140 150
YEGPDLAEQA IYFSAAVLET LKVLDLQMDV LHVNDWQTSL IPVYLKTLYK
160 170 180 190 200
EDEFYAKTVT LLTIHNLGYQ GIFDSKYMEF SGLPNYLYNI DGIEFYGKIN
210 220 230 240 250
FLKGGILYSD IINTVSPTYA NEIQTKEYGE KLDGVLRLRS ADLYGVLNGI
260 270 280 290 300
DYDEYNPETD KRIFVNYSLD NIDKKYENKV RLQKELGLPE DRRIPMIGMI
310 320 330 340 350
TRLVDQKGLD ILSEVLRYIV NYDIQFVILG TGDEKYEEMF KKAQQEFPKN
360 370 380 390 400
VSANVKFDIN LAQKIYAASD MFLMPSRYEP CGLGQMYSLR YGTIPIVRYT
410 420 430 440 450
GGLADTVLEY DENKMTGNGF GFVEYDSSKL LKAVARALDF YKNKKVHWKK
460 470 480
LIDNAMKTDL SWERSAKEYV KLYNKAMSKR I
Length:481
Mass (Da):55,404
Last modified:July 24, 2007 - v1
Checksum:i7DFB61188071338B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000716 Genomic DNA. Translation: ABR29954.1.
RefSeqiWP_012056316.1. NC_009616.1.
YP_001305339.1. NC_009616.1.

Genome annotation databases

EnsemblBacteriaiABR29954; ABR29954; Tmel_0077.
GeneIDi5297297.
KEGGitme:Tmel_0077.
PATRICi23921241. VBITheMel19269_0082.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000716 Genomic DNA. Translation: ABR29954.1.
RefSeqiWP_012056316.1. NC_009616.1.
YP_001305339.1. NC_009616.1.

3D structure databases

ProteinModelPortaliA6LJ53.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391009.Tmel_0077.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR29954; ABR29954; Tmel_0077.
GeneIDi5297297.
KEGGitme:Tmel_0077.
PATRICi23921241. VBITheMel19269_0082.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciTMEL391009:GHM1-82-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BI429 / DSM 12029.

Entry informationi

Entry nameiGLGA_THEM4
AccessioniPrimary (citable) accession number: A6LJ53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: February 4, 2015
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.