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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDIS435591:G1G5A-3693-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BDI_3601
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesTannerellaceaeParabacteroides
Proteomesi
  • UP000000566 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180821 – 597Arginine--tRNA ligaseAdd BLAST597

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi435591.BDI_3601

Structurei

3D structure databases

ProteinModelPortaliA6LHY5
SMRiA6LHY5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi125 – 135"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A6LHY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVIEQQITGA IIAGIKELYG ADVTASQVQL QKTKKEFKGH LTLVVFPFLR
60 70 80 90 100
MSKKSPEQTA QEIGEYLLRN EPAVAEFNVI KGFLNLTVAC SCWIDLLNSI
110 120 130 140 150
NEQPAYGIIP VTEQSPLVMI EYSSPNTNKP LHLGHVRNNL LGYSLSKIIK
160 170 180 190 200
ANGNQIVKTN IVNDRGIHIC KSMLAWQKWG NGATPESTGK KGDHLIGDFY
210 220 230 240 250
VLFSNKLKEE THALEAKGLT KEEAEAQSTL MAEAREMLRK WEAGDKEVRA
260 270 280 290 300
LWEMMNNWVY AGFNETYKMM GVDFDKIYYE SQTYLEGKGK VMEGLEKGIF
310 320 330 340 350
YRREDGSVWA DLTKDGLDEK LLLRADGTSV YMTQDIGTAK LRFDDYPINK
360 370 380 390 400
MIYVVGNEQN YHFQVLSILL DKLGFEFGKG LVHFSYGMVE LPEGKMKSRE
410 420 430 440 450
GTVVDADDLM AEMISTAREI SQELGKLDEM TPEEAENIAR IVGLGSLKYF
460 470 480 490 500
ILKVDPRKNM TFNPKESIDF NGNTGPFIQY TYARIRSVLR KAAEQGIVLP
510 520 530 540 550
EQLPLTFAIS EKEENLIQMI ADYAEIVKEA GKLYSPACVA NYIYDLVKEY
560 570 580 590
NQFYHDFSIL REENPELKNF RLVLSANVAK IVKSGMDLLG IEVPERM
Length:597
Mass (Da):67,557
Last modified:July 24, 2007 - v1
Checksum:i0319967D867C68B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA Translation: ABR45299.1
RefSeqiWP_012056086.1, NC_009615.1

Genome annotation databases

EnsemblBacteriaiABR45299; ABR45299; BDI_3601
GeneIDi5308750
KEGGipdi:BDI_3601
PATRICifig|435591.13.peg.3564

Similar proteinsi

Entry informationi

Entry nameiSYR_PARD8
AccessioniPrimary (citable) accession number: A6LHY5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: February 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome