Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A6LG40 (A6LG40_PARD8) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Ordered Locus Names:BDI_2946 EMBL ABR44654.1
OrganismParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) [Complete proteome] [HAMAP] EMBL ABR44654.1
Taxonomic identifier435591 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaeParabacteroides

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   LigandChloride PDB 4FJ6
   Molecular functionHydrolase EMBL ABR44654.1
   Technical term3D-structure PDB 4FJ6
Complete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: InterPro

   Molecular_functionexo-alpha-sialidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region89 – 902Phosphate 1 binding PDB 4FJ6

Sites

Binding site261Phosphate 1 PDB 4FJ6
Binding site1091Chloride 2; via amide nitrogen PDB 4FJ6
Binding site2001Phosphate 2 PDB 4FJ6
Binding site2361Phosphate 4 PDB 4FJ6
Binding site2361Phosphate 5 PDB 4FJ6
Binding site2451Phosphate 5 PDB 4FJ6
Binding site2611Phosphate 3 PDB 4FJ6
Binding site3211Phosphate 4 PDB 4FJ6
Binding site3211Phosphate 5 PDB 4FJ6
Binding site3841Phosphate 6 PDB 4FJ6
Binding site4111Phosphate 2 PDB 4FJ6
Binding site4751Phosphate 2 PDB 4FJ6
Binding site5061Phosphate 2 PDB 4FJ6

Sequences

Sequence LengthMass (Da)Tools
A6LG40 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 0EBE5CECA9F394CD

FASTA54160,191
        10         20         30         40         50         60 
MKKTFLYFCL LFIVQTAFAA DSIYVREQQI PILIDRIDNV LYEMRIPAQK GDVLNEITIQ 

        70         80         90        100        110        120 
IGDNVDLSDI QAIRLFYSGV EAPSRKGEHF SPVTYISSHI PGNTRKALES YSVRQDEVTA 

       130        140        150        160        170        180 
PLSRTVKLTS KQPMLKGINY FWVSIQMKPE TSLLAKVATT MPNAQINNKP INITWKGKVD 

       190        200        210        220        230        240 
ERHVGIGVRQ AGDDGSAAFR IPGLVTTNNG TLLGVYDIRY NSSVDLQEKI DIGVSRSTDK 

       250        260        270        280        290        300 
GQTWEPMRVA MTFKQTDGLP HGQNGVGDPS ILVDEKTNTI WVVAAWTHGM GNERAWWNSM 

       310        320        330        340        350        360 
PGMTPDETAQ LMLVKSEDDG KTWSEPINIT SQVKDPSWYF LLQGPGRGIT MQDGTLVFPI 

       370        380        390        400        410        420 
QFIDATRVPN AGIMYSKDRG KTWHLHNLAR TNTTEAQVAE VEPGVLMLNM RDNRGGSRAV 

       430        440        450        460        470        480 
ATTKDLGKTW TEHPSSRSAL QESVCMASLI KVNAKDNITG KDLLLFSNPN TTKGRNHITI 

       490        500        510        520        530        540 
KASLDGGLTW PTEHQVLLDE AEGWGYSCLS MIDKETVGIF YESSVAHMTF QAVKLQDLIH 


Q 

« Hide

References

« Hide 'large scale' references
[1]"Evolution of symbiotic bacteria in the distal human intestine."
Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I.
PLoS Biol. 5:1574-1586(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 8503 / DSM 20701 / NCTC 11152.
[2]"Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution."
JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)
Submitted (JUN-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) OF 20-541 IN COMPLEX WITH CHLORIDE AND PHOSPHATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000140 Genomic DNA. Translation: ABR44654.1.
RefSeqYP_001304276.1. NC_009615.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4FJ6X-ray1.90A/B/C/D20-541[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING435591.BDI_2946.

Protein family/group databases

CAZyGH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR44654; ABR44654; BDI_2946.
GeneID5308095.
KEGGpdi:BDI_2946.
PATRIC22849100. VBIParDis29947_2908.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4409.
HOGENOMHOG000252336.
KOK01186.
OMAMYLAREC.
OrthoDBEOG67DPK3.
ProtClustDBCLSK822190.

Enzyme and pathway databases

BioCycPDIS435591:GCNH-2940-MONOMER.

Family and domain databases

Gene3D2.120.10.10. 1 hit.
InterProIPR026948. Sialidase/anhydrosialidase.
IPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSPR01803. TCSIALIDASE.
SUPFAMSSF50939. SSF50939. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA6LG40_PARD8
AccessionPrimary (citable) accession number: A6LG40
Entry history
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)