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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei144GTPUniRule annotation1
Binding sitei148GTPUniRule annotation1
Binding sitei191GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 29GTPUniRule annotation5
Nucleotide bindingi113 – 115GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:BDI_2483Imported
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)Imported
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesTannerellaceaeParabacteroides
Proteomesi
  • UP000000566 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi435591.BDI_2483.

Structurei

3D structure databases

ProteinModelPortaliA6LET9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 209TubulinInterPro annotationAdd BLAST193
Domaini211 – 330Tubulin_CInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili330 – 360Sequence analysisAdd BLAST31

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiIMNQGGV.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LET9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDTILNFNY PTDTPKIIKV IGVGGGGGNA VTHMYKEGIH DVTFVLCNTD
60 70 80 90 100
NQALNRSDVP IKLLLGREIT QGLGAGNKPE RAMMAAEESL DDLRGMLNDG
110 120 130 140 150
TKMVFITAGM GGGTGTGAAP VIARIAKDMG ILTVGIVTIP FLFEGERKII
160 170 180 190 200
QALNGVEEIA KNVDALLVIN NERLREIYSD LSVMNAFGKA DDTLTIAAKS
210 220 230 240 250
IAEIITLPGI INLDFADVNT TMKDGGVALM SNGFGEGEGR VRQAVEDALN
260 270 280 290 300
SPLLSNNDVK NAKKILFNVY FSEEAELRME EMNDVHNFMS EFNRDIEVIW
310 320 330 340 350
GTAVDNTLGN KVKMTILATG FTMDDIPLIA DKRRNEAAQM TEEELRLEEE
360 370 380 390 400
RIEKERKERD LIGKYYGASA QKAGRFTSRA KAVVLTQEEL DDDALIALIE
410 420 430 440 450
DNPTYNRDPK IVARARSKVA GEDIQVSAPT TAKQPANQPR QDSQRGGKQV

ISFR
Length:454
Mass (Da):49,613
Last modified:July 24, 2007 - v1
Checksum:iAF3BB9924055E9C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR44203.1.
RefSeqiWP_005866974.1. NC_009615.1.

Genome annotation databases

EnsemblBacteriaiABR44203; ABR44203; BDI_2483.
GeneIDi5307632.
KEGGipdi:BDI_2483.

Similar proteinsi

Entry informationi

Entry nameiA6LET9_PARD8
AccessioniPrimary (citable) accession number: A6LET9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: October 25, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported