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A6LDS0

- PYRF_PARD8

UniProt

A6LDS0 - PYRF_PARD8

Protein

Orotidine 5'-phosphate decarboxylase

Gene

pyrF

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (24 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei96 – 961Proton donorUniRule annotation

    GO - Molecular functioni

    1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    BioCyciPDIS435591:GCNH-2097-MONOMER.
    UniPathwayiUPA00070; UER00120.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Orotidine 5'-phosphate decarboxylaseUniRule annotation (EC:4.1.1.23UniRule annotation)
    Alternative name(s):
    OMP decarboxylaseUniRule annotation
    Short name:
    OMPDCaseUniRule annotation
    Short name:
    OMPdecaseUniRule annotation
    Gene namesi
    Name:pyrFUniRule annotation
    Ordered Locus Names:BDI_2103
    OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
    Taxonomic identifieri435591 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaeParabacteroides
    ProteomesiUP000000566: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 280280Orotidine 5'-phosphate decarboxylasePRO_1000138957Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi435591.BDI_2103.

    Structurei

    3D structure databases

    ProteinModelPortaliA6LDS0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the OMP decarboxylase family. Type 2 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0284.
    HOGENOMiHOG000245747.
    KOiK01591.
    OMAiCRTSNAG.
    OrthoDBiEOG6DZF33.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_01215. OMPdecase_type2.
    InterProiIPR013785. Aldolase_TIM.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00215. OMPdecase. 1 hit.
    [Graphical view]
    SMARTiSM00934. OMPdecase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6LDS0-1 [UniParc]FASTAAdd to Basket

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    MNKQQLFENI KKKQSFLCVG LDTDIKKIPQ HLLSEEDPIF AFNKAIIDAT    50
    ADYCVAYKPN LAFYESLGTK GMMAFEKTVA YLRENYPDQF IIADAKRGDI 100
    GNTSEMYARS FFDHIKVDAV TVAPYMGEDS VKPFLIYPEA WVILLALTSN 150
    KGSHDFQMTE DANGERLFEK VLKKSQEWAN DEQMMYVVGA TQGKMFLDIR 200
    KQAPNHFLLV PGVGAQGGSL AEVAQYGMND QCGLLVNSSR AIIYADKTEA 250
    FANVAREAAH AVQKEMAGYL HDKGIIPCKA 280
    Length:280
    Mass (Da):31,263
    Last modified:July 24, 2007 - v1
    Checksum:iD234180F1706413F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000140 Genomic DNA. Translation: ABR43834.1.
    RefSeqiYP_001303456.1. NC_009615.1.

    Genome annotation databases

    EnsemblBacteriaiABR43834; ABR43834; BDI_2103.
    GeneIDi5307252.
    KEGGipdi:BDI_2103.
    PATRICi22847414. VBIParDis29947_2088.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000140 Genomic DNA. Translation: ABR43834.1 .
    RefSeqi YP_001303456.1. NC_009615.1.

    3D structure databases

    ProteinModelPortali A6LDS0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 435591.BDI_2103.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR43834 ; ABR43834 ; BDI_2103 .
    GeneIDi 5307252.
    KEGGi pdi:BDI_2103.
    PATRICi 22847414. VBIParDis29947_2088.

    Phylogenomic databases

    eggNOGi COG0284.
    HOGENOMi HOG000245747.
    KOi K01591.
    OMAi CRTSNAG.
    OrthoDBi EOG6DZF33.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00120 .
    BioCyci PDIS435591:GCNH-2097-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_01215. OMPdecase_type2.
    InterProi IPR013785. Aldolase_TIM.
    IPR011995. OMPdecase_type-2.
    IPR001754. OMPdeCOase_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00215. OMPdecase. 1 hit.
    [Graphical view ]
    SMARTi SM00934. OMPdecase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 8503 / DSM 20701 / NCTC 11152.

    Entry informationi

    Entry nameiPYRF_PARD8
    AccessioniPrimary (citable) accession number: A6LDS0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3