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Protein
Submitted name:

Putative NADH dehydrogenase/NAD(P)H nitroreductase

Gene

BDI_1728

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei65 – 651FMN; via amide nitrogenCombined sources
Binding sitei92 – 921FMN; via carbonyl oxygenCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi37 – 415FMNCombined sources
Nucleotide bindingi140 – 1423FMNCombined sources
Nucleotide bindingi181 – 1833FMNCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Flavoprotein, FMNCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciPDIS435591:GCNH-1724-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative NADH dehydrogenase/NAD(P)H nitroreductaseImported
Gene namesi
Ordered Locus Names:BDI_1728Imported
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)Imported
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaeParabacteroides
Proteomesi
  • UP000000566 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 194171Sequence analysisPRO_5002698714Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi435591.BDI_1728.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3M5KX-ray1.86A/B24-194[»]
ProteinModelPortaliA6LCR1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA6LCR1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini34 – 8855NitroreductaseInterPro annotationAdd
BLAST
Domaini116 – 17358NitroreductaseInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108ZWN. Bacteria.
COG0778. LUCA.
HOGENOMiHOG000146732.
OMAiAPREERM.
OrthoDBiEOG64JFVW.

Family and domain databases

Gene3Di3.40.109.10. 1 hit.
InterProiIPR029479. Nitroreductase.
IPR000415. Nitroreductase-like.
[Graphical view]
PfamiPF00881. Nitroreductase. 2 hits.
[Graphical view]
SUPFAMiSSF55469. SSF55469. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LCR1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRICLFFLIT VFLMACSSTG NQRQEPENQT LETILNRKSV RKYKDRPVEK
60 70 80 90 100
EKIDKLIRAG MAAPSSRDRR PWEFIIVTDR KALDTMAEGL PFARMLKETR
110 120 130 140 150
QAIVVCGDTI KSSNAWFLDC SAASQNLLLA AESMGLGAVW TAVYPYPDRI
160 170 180 190
EIVRKELRLP DHIMPLNVIP VGYPMQKETP KNKYNVQQIH HNGW
Length:194
Mass (Da):22,249
Last modified:July 24, 2007 - v1
Checksum:i067C74F311E09F4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR43475.1.
RefSeqiWP_008779572.1. NC_009615.1.

Genome annotation databases

EnsemblBacteriaiABR43475; ABR43475; BDI_1728.
GeneIDi5306879.
KEGGipdi:BDI_1728.
PATRICi22846648. VBIParDis29947_1717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR43475.1.
RefSeqiWP_008779572.1. NC_009615.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3M5KX-ray1.86A/B24-194[»]
ProteinModelPortaliA6LCR1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi435591.BDI_1728.

Protocols and materials databases

DNASUi5306879.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR43475; ABR43475; BDI_1728.
GeneIDi5306879.
KEGGipdi:BDI_1728.
PATRICi22846648. VBIParDis29947_1717.

Phylogenomic databases

eggNOGiENOG4108ZWN. Bacteria.
COG0778. LUCA.
HOGENOMiHOG000146732.
OMAiAPREERM.
OrthoDBiEOG64JFVW.

Enzyme and pathway databases

BioCyciPDIS435591:GCNH-1724-MONOMER.

Miscellaneous databases

EvolutionaryTraceiA6LCR1.

Family and domain databases

Gene3Di3.40.109.10. 1 hit.
InterProiIPR029479. Nitroreductase.
IPR000415. Nitroreductase-like.
[Graphical view]
PfamiPF00881. Nitroreductase. 2 hits.
[Graphical view]
SUPFAMiSSF55469. SSF55469. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8503 / DSM 20701 / NCTC 11152Imported.
  2. "Crystal structure of Putative NADH dehydrogenase/NAD(P)H nitroreductase (BDI_1728) from Parabacteroides distasonis ATCC 8503 at 1.86 A resolution."
    Joint Center for Structural Genomics (JCSG)
    Submitted (MAR-2010) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.86 ANGSTROMS) OF 24-194 IN COMPLEX WITH FMN.

Entry informationi

Entry nameiA6LCR1_PARD8
AccessioniPrimary (citable) accession number: A6LCR1
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: March 16, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.