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Protein

Glutaminase

Gene

glsA

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei69 – 691SubstrateUniRule annotation
Binding sitei120 – 1201SubstrateUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Binding sitei172 – 1721SubstrateUniRule annotation
Binding sitei196 – 1961SubstrateUniRule annotation
Binding sitei248 – 2481SubstrateUniRule annotation
Binding sitei266 – 2661Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPDIS435591:GCNH-819-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:BDI_0820
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaeParabacteroides
ProteomesiUP000000566 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlutaminasePRO_1000048338Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi435591.BDI_0820.

Structurei

3D structure databases

ProteinModelPortaliA6LA76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiPMNPMVN.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A6LA76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKKITIAQI KEVAQQAYDL YKTNTDGKNA DYIPYLANIN KNLFGISICL
60 70 80 90 100
LNGQTIEVGD SEYRFGIESV SKVHTAILVL RQYGAKELLE KIGADATGLP
110 120 130 140 150
FNSIIAILLE NDHPSTPLVN AGAITACSMV KPVGDSKQKW DAIVANITDL
160 170 180 190 200
CGSAPQLIDE LYKSESATNF NNRSIAWLLK NYNRIYDDPD MSLDLYTRQC
210 220 230 240 250
SLGITAKQLS VAAATVANLG LNPVTKKQVF DAELSPKITS MISTVGFYEH
260 270 280 290 300
TGDWLYTSGI PAKTGVGGGV MGVLPGQFGI SAFAPPIDQA GNSVKAQLAI
310 320
KYVMNKLGLN VFNGHRVTIV D
Length:321
Mass (Da):34,670
Last modified:July 24, 2007 - v1
Checksum:i4E46223836EFAB4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR42590.1.
RefSeqiWP_005857387.1. NC_009615.1.

Genome annotation databases

EnsemblBacteriaiABR42590; ABR42590; BDI_0820.
GeneIDi5305974.
KEGGipdi:BDI_0820.
PATRICi22844782. VBIParDis29947_0800.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR42590.1.
RefSeqiWP_005857387.1. NC_009615.1.

3D structure databases

ProteinModelPortaliA6LA76.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi435591.BDI_0820.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR42590; ABR42590; BDI_0820.
GeneIDi5305974.
KEGGipdi:BDI_0820.
PATRICi22844782. VBIParDis29947_0800.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiPMNPMVN.
OrthoDBiEOG6N94BK.

Enzyme and pathway databases

BioCyciPDIS435591:GCNH-819-MONOMER.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8503 / DSM 20701 / NCTC 11152.

Entry informationi

Entry nameiGLSA_PARD8
AccessioniPrimary (citable) accession number: A6LA76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: July 22, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.