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Protein

Xylose isomerase

Gene

xylA

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei107UniRule annotation1
Active sitei110UniRule annotation1
Metal bindingi238Magnesium 1UniRule annotation1
Metal bindingi274Magnesium 1UniRule annotation1
Metal bindingi274Magnesium 2UniRule annotation1
Metal bindingi277Magnesium 2UniRule annotation1
Metal bindingi302Magnesium 1UniRule annotation1
Metal bindingi313Magnesium 2UniRule annotation1
Metal bindingi315Magnesium 2UniRule annotation1
Metal bindingi345Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPDIS435591:G1G5A-803-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BDI_0783Imported
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)Imported
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesTannerellaceaeParabacteroides
Proteomesi
  • UP000000566 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi435591.BDI_0783

Structurei

3D structure databases

ProteinModelPortaliA6LA39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

A6LA39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYFKGEKEF FPGIGQIQFE GRESKNPLAF HYYDADKVVM GKTLKDHLRF
60 70 80 90 100
AMAYWHTLCA EGGDQFGGGT KTFPWNDSTD AITRAKYKMD AAFEFMTKCN
110 120 130 140 150
IPYYCFHDVD VVDEAPTLGE FEKRLQTMVE HAKEHQAATG KKLLWSTANV
160 170 180 190 200
FGHKRYMNGA ATNPYFPTVA CVGTQIKNAI DACIALGGEN YVFWGGREGY
210 220 230 240 250
MSLLNTNMKR EKDHLAMMLT MARDYGRKNG FKGTFLIEPK PMEPTKHQYD
260 270 280 290 300
VDSETVIGFL RHYGLDKDFA LNIEVNHATL AGHTFEHELQ AAADAGMLCS
310 320 330 340 350
IDANRGDYQN GWDTDQFPMD IYELAQAWLV ILEGGGLTTG GTNFDAKTRR
360 370 380 390 400
NSTDLEDIFI AHIGGMDAFA RALMIAADIL ENSDYRKMRA ERYASFDAGE
410 420 430 440
GKAFEDGKLT LEDLRTIALR DGEPKQISGK QELYEMIVNL HI
Length:442
Mass (Da):49,782
Last modified:July 24, 2007 - v1
Checksum:i840F96B5BA5B23B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA Translation: ABR42553.1
RefSeqiWP_011966163.1, NC_009615.1

Genome annotation databases

EnsemblBacteriaiABR42553; ABR42553; BDI_0783
GeneIDi5305937
KEGGipdi:BDI_0783
PATRICifig|435591.13.peg.762

Similar proteinsi

Entry informationi

Entry nameiA6LA39_PARD8
AccessioniPrimary (citable) accession number: A6LA39
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: April 25, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health