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A6LA39

- A6LA39_PARD8

UniProt

A6LA39 - A6LA39_PARD8

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Protein

Xylose isomerase

Gene

xylA

Organism
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei107 – 1071UniRule annotation
Active sitei110 – 1101UniRule annotation
Metal bindingi238 – 2381Magnesium 1UniRule annotation
Metal bindingi274 – 2741Magnesium 1UniRule annotation
Metal bindingi274 – 2741Magnesium 2UniRule annotation
Metal bindingi277 – 2771Magnesium 2UniRule annotation
Metal bindingi302 – 3021Magnesium 1UniRule annotation
Metal bindingi313 – 3131Magnesium 2UniRule annotation
Metal bindingi315 – 3151Magnesium 2UniRule annotation
Metal bindingi345 – 3451Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPDIS435591:GCNH-782-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:BDI_0783Imported
OrganismiParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152)Imported
Taxonomic identifieri435591 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPorphyromonadaceaeParabacteroides
ProteomesiUP000000566: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi435591.BDI_0783.

Structurei

3D structure databases

ProteinModelPortaliA6LA39.
SMRiA6LA39. Positions 8-442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000252293.
KOiK01805.
OMAiLFHAHIG.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6LA39-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYFKGEKEF FPGIGQIQFE GRESKNPLAF HYYDADKVVM GKTLKDHLRF
60 70 80 90 100
AMAYWHTLCA EGGDQFGGGT KTFPWNDSTD AITRAKYKMD AAFEFMTKCN
110 120 130 140 150
IPYYCFHDVD VVDEAPTLGE FEKRLQTMVE HAKEHQAATG KKLLWSTANV
160 170 180 190 200
FGHKRYMNGA ATNPYFPTVA CVGTQIKNAI DACIALGGEN YVFWGGREGY
210 220 230 240 250
MSLLNTNMKR EKDHLAMMLT MARDYGRKNG FKGTFLIEPK PMEPTKHQYD
260 270 280 290 300
VDSETVIGFL RHYGLDKDFA LNIEVNHATL AGHTFEHELQ AAADAGMLCS
310 320 330 340 350
IDANRGDYQN GWDTDQFPMD IYELAQAWLV ILEGGGLTTG GTNFDAKTRR
360 370 380 390 400
NSTDLEDIFI AHIGGMDAFA RALMIAADIL ENSDYRKMRA ERYASFDAGE
410 420 430 440
GKAFEDGKLT LEDLRTIALR DGEPKQISGK QELYEMIVNL HI
Length:442
Mass (Da):49,782
Last modified:July 24, 2007 - v1
Checksum:i840F96B5BA5B23B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR42553.1.
RefSeqiWP_011966163.1. NC_009615.1.
YP_001302175.1. NC_009615.1.

Genome annotation databases

EnsemblBacteriaiABR42553; ABR42553; BDI_0783.
GeneIDi5305937.
KEGGipdi:BDI_0783.
PATRICi22844706. VBIParDis29947_0762.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000140 Genomic DNA. Translation: ABR42553.1 .
RefSeqi WP_011966163.1. NC_009615.1.
YP_001302175.1. NC_009615.1.

3D structure databases

ProteinModelPortali A6LA39.
SMRi A6LA39. Positions 8-442.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 435591.BDI_0783.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABR42553 ; ABR42553 ; BDI_0783 .
GeneIDi 5305937.
KEGGi pdi:BDI_0783.
PATRICi 22844706. VBIParDis29947_0762.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000252293.
KOi K01805.
OMAi LFHAHIG.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci PDIS435591:GCNH-782-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 8503 / DSM 20701 / NCTC 11152Imported.

Entry informationi

Entry nameiA6LA39_PARD8
AccessioniPrimary (citable) accession number: A6LA39
Entry historyi
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: November 26, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3