A6L996 (A6L996_PARD8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

BDI_0483

Organism

Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) [Complete proteome] [HAMAP]

Taxonomic identifier

435591 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Parabacteroides

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6L996 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: F47FD9DBFE029F23	FASTA	364	38,653
	10 20 30 40 50 60 MIIGIPKEIK NNENRVALTP AGAKELVKRG HTVYVQHTAG INSGFADDAY VAAGARILPS 70 80 90 100 110 120 IEDVYGIAEM IVKVKEPIAS EYPLVRKGQL VFTYFHFASD EALTLAMIKS GSICLAYETV 130 140 150 160 170 180 ENPDHTLPLL IPMSEVAGRM SVQEGARFLE KPQGGKGVLL GGVPGVKPGK VLVLGGGVVG 190 200 210 220 230 240 HNAALMAAGL GADVTIADIS LPRLRYLSET MPKNVKTLFS STHTIEQELP TTDLVIGAVL 250 260 270 280 290 300 IPGAKAPHLI TRDMLKLLKP GSVLVDVAID QGGCFETSHP TTHANPVYEI DDILHYCVAN 310 320 330 340 350 360 IPGAVPQTST LALTNATLPY VIKLADRGWE KACEEDPGLE LGLNIVEGKI VYPAVAEAFP SLKA

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000140 Genomic DNA. Translation: ABR42260.1.
RefSeq	YP_001301882.1. NC_009615.1.
3D structure databases
ProteinModelPortal	A6L996.
SMR	A6L996. Positions 1-362.
ModBase	Search...
Protein-protein interaction databases
STRING	A6L996.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5305638.
GenomeReviews	Gene locus BDI_0483 in contig CP000140_GR.
KEGG	pdi:BDI_0483.
PATRIC	22844114. VBIParDis29947_0470.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0686.
HOGENOM	HBG289735.
OMA	AIGYETV.
ProtClustDB	CLSK822772.
Enzyme and pathway databases
BioCyc	PDIS435591:BDI_0483-MONOMER.
Family and domain databases
InterPro	IPR008142. Ala_DH/PNT_CS1. IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00836. ALADH_PNT_1. 1 hit. PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6L996_PARD8

Accession

Primary (citable) accession number: A6L996

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)