A6L8Z0 (A6L8Z0_PARD8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Mannonate dehydratase HAMAP MF_00106
EC=4.2.1.8 HAMAP MF_00106

Alternative name(s):
D-mannonate hydrolase HAMAP MF_00106

Gene names

Name:	uxuA HAMAP MF_00106
Ordered Locus Names:	BDI_0376

Organism

Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) [Complete proteome] [HAMAP]

Taxonomic identifier

435591 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Parabacteroides

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106 SAAS SAAS004628
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106 SAAS SAAS004628
Sequence similarities	Belongs to the mannonate dehydratase family. HAMAP MF_00106

Ontologies

Keywords
Molecular function	Lyase HAMAP MF_00106 SAAS SAAS004628
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucuronate catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	mannonate dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6L8Z0 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 09D8957205A72325	FASTA	392	44,708
	10 20 30 40 50 60 MYLCEQTWRW YGPNDPVSLW DIRQAGATGI VNALHHIPNG EVWTTEEIQK RKALIESAGL 70 80 90 100 110 120 RWSVVESVPV HEHIKTQTGD FQTYIENYKQ SIRNLGACDI RVVTYNFMPV LDWTRTDLAY 130 140 150 160 170 180 TMPDGSKALR FERAAFMAFD LFILKRPAAE AEYTEADKAK AKARYDAMSE EDRQLLVRNM 190 200 210 220 230 240 IAGLPGSEET FTIEQFREAL DRYKDIDAER LRSNLIYFLR EIAPVADEAG VKLVIHPDDP 250 260 270 280 290 300 PYSILGLPRI LSTEDDFRKL IEAVPNPSNG LCLCTGSFGV RSDNDLAGIM ERYGDRIDFV 310 320 330 340 350 360 HFRSTQRDSE GNFFEANHLE GDVDMYGVMK AFLELQQRRQ CSIAMRPDHG HQMIDDLKKK 370 380 390 TNPGYSCIGR LRGLAELRGL EMGIALSLFK GH

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000140 Genomic DNA. Translation: ABR42154.1.
RefSeq	YP_001301776.1. NC_009615.1.
3D structure databases
ProteinModelPortal	A6L8Z0.
ModBase	Search...
Protein-protein interaction databases
STRING	A6L8Z0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5305531.
GenomeReviews	Gene locus BDI_0376 in contig CP000140_GR.
KEGG	pdi:BDI_0376.
PATRIC	22843902. VBIParDis29947_0365.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1312.
HOGENOM	HBG585927.
OMA	VHEEIKT.
ProtClustDB	PRK03906.
Enzyme and pathway databases
BioCyc	PDIS435591:BDI_0376-MONOMER.
Family and domain databases
HAMAP	MF_00106. UxuA. [Tree]
InterPro	IPR004628. Man_deHydtase. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Gene3D	G3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KO	K01686.
Pfam	PF03786. UxuA. 1 hit. [Graphical view]
PIRSF	PIRSF016049. Man_dehyd. 1 hit.
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00695. UxuA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6L8Z0_PARD8

Accession

Primary (citable) accession number: A6L8Z0

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)