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A6L7Y2 (A6L7Y2_PARD8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377
Gene names
Name:dnaA HAMAP MF_00377
Ordered Locus Names:BDI_0001
OrganismParabacteroides distasonis (strain ATCC 8503 / DSM 20701 / NCTC 11152) [Complete proteome] [HAMAP]
Taxonomic identifier435591 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Porphyromonadaceae › Parabacteroides

Protein attributes

Sequence length465 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577

Subcellular location

Cytoplasm By similarity HAMAP MF_00377.

Sequence similarities

Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding170 – 1778ATP By similarity HAMAP MF_00377

Sequences

Sequence LengthMass (Da)Tools
A6L7Y2 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 48B26ECB8ED1CB69

FASTA46553,203
        10         20         30         40         50         60 
MQTDYQTLWN KCLAVIKDIV PKAAFDTWFV PIVPLSYEDK KFTIQVPSQF FYEYLEEKYV 

        70         80         90        100        110        120 
NVLKVTLYRV IGQGTILNYR IMVDKTTGGT VDYPAENAST AVKKVTPKDA NKAPNPFMTT 

       130        140        150        160        170        180 
APQDLDPQLN PKYNFDNYFE GTSNKLVRTA GEAVAQNPGK TTFNPLFIFG PSGVGKTHLC 

       190        200        210        220        230        240 
HAIGTRIREL HPEKKVLYVS SHLFRVQFTD AIRKNTTNDF LNFYQNIDVL LLDDIQELIG 

       250        260        270        280        290        300 
MDKTQNTFFH IFNHLHQLGK QLILTSDKPP VDLQGMEERL ITRLKWGLTA ELSRPDLDLR 

       310        320        330        340        350        360 
KKILKNKINH DGIMIPDEVF NFIANNVTEN VRDLEGILVS LMANAVINNR EIDLPLTKRV 

       370        380        390        400        410        420 
VSQAVRLEKK QISVQMIQEI VCKYFNLEQS VIQTNSRKRE IVQARQITMY LAKKYTDSSF 

       430        440        450        460 
SHIGKIVGKK DHATVLHACK TIKDQIETSK SFRSSVEEIE VLLKN

« Hide

References

[1]"Evolution of symbiotic bacteria in the distal human intestine."
Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I.
PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000140 Genomic DNA. Translation: ABR41796.1.
RefSeqYP_001301418.1. NC_009615.1.

3D structure databases

ProteinModelPortalA6L7Y2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6L7Y2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5305156.
GenomeReviewsGene locus BDI_0001 in contig CP000140_GR.
KEGGpdi:BDI_0001.
PATRIC22843140. VBIParDis29947_0001.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0593.
HOGENOMHBG695666.
OMACHTLNAL.
ProtClustDBPRK00149.

Enzyme and pathway databases

BioCycPDIS435591:BDI_0001-MONOMER.

Family and domain databases

HAMAPMF_00377. DnaA_bact.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
Gene3DG3DSA:1.10.1750.10. DnaA_C. 1 hit.
KOK02313.
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMSSF48295. Trp_repress_rep. 1 hit.
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA6L7Y2_PARD8
AccessionPrimary (citable) accession number: A6L7Y2
Entry history
Integrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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