Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot A6L792 (XYLA_BACV8)

Last modified November 3, 2009. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: BVU_3953
OrganismBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]
Taxonomic identifier435590 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Hide | Top

Protein attributes

Sequence length438 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

Hide | Top

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 438438Xylose isomerase HAMAP MF_00455
PRO_1000026430

Sites

Active site1031 By similarity
Active site1061 By similarity
Metal binding2341Magnesium 1 By similarity
Metal binding2701Magnesium 1 By similarity
Metal binding2701Magnesium 2 By similarity
Metal binding2731Magnesium 2 By similarity
Metal binding2981Magnesium 1 By similarity
Metal binding3091Magnesium 2 By similarity
Metal binding3111Magnesium 2 By similarity
Metal binding3411Magnesium 1 By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
A6L792-1 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: F1AC973EF3A2F230

FASTA43849,036
        10         20         30         40         50         60 
MATKEYFPGI GKIKFEGKES KNPMAFRYYD AEKVINGKKM KDWLKFAMAW WHTLCAEGGD 

        70         80         90        100        110        120 
QFGGGTKKFP WNGDADKVQA AKNKMDAGFE FMQKMGIEYY CFHDVDLCEE ADTIEEYEAN 

       130        140        150        160        170        180 
LKEIVAYAKQ KQAETGIKLL WGTANVFGHA RYMNGAATNP EFDVVARAAV QIKNAIDATI 

       190        200        210        220        230        240 
ELGGSNYVFW GGREGYMSLL NTDQKREKEH LAQMLTIARD YARSKGFTGT FLIEPKPMEP 

       250        260        270        280        290        300 
TKHQYDVDTE TVVGFLKTHG LDKDFKVNIE VNHATLAGHT FEHELAVAVD NGMLGSIDAN 

       310        320        330        340        350        360 
RGDYQNGWDT DQFPIDNYEL TQAMMQIIRN GGLGNGGTNF DAKTRRNSTD LEDIFIAHIA 

       370        380        390        400        410        420 
GMDAMARALE SAAALLNESP YCKMLSDRYA SFDSGKGKEF EEGKLTLEDV VAYAKQNGEP 

       430 
KQVSGKQELY EAIVNMYC

« Hide

Hide | Top

References

[1]"Evolution of symbiotic bacteria in the distal human intestine."
Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I.
PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Hide | Top

Cross-references

Sequence databases

CP000139 Genomic DNA. Translation: ABR41556.1.
RefSeqYP_001301178.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA6L792.

Genome annotation databases

GeneID5304912.
GenomeReviewsGene locus BVU_3953 in contig CP000139_GR.
KEGGbvu:BVU_3953.
NMPDRfig|435590.6.peg.3670.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQFLIEPK.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameXYLA_BACV8
AccessionPrimary (citable) accession number: A6L792
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: November 3, 2009
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents