A6L6V4 (A6L6V4_BACV8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183

Gene names

Ordered Locus Names:

BVU_3807

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183
Pathway	Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183
Sequence similarities	Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
Ligand	NAD PIRNR PIRNR000183
Molecular function	Oxidoreductase PIRNR PIRNR000183
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alanine dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6L6V4 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: FF2A4E9AC3FB93FE	FASTA	363	38,996
	10 20 30 40 50 60 MIVGIPKEIK NNENRVSLTP AGAHELVQRG HTVYIQHTAG INSGFSDEEY EKVGARILPT 70 80 90 100 110 120 IEDVYAIAEM IIKVKEPIEC EYNLVRKGQL VFTYFHFACD KELTEAMMRS GSVCLAYETV 130 140 150 160 170 180 TDKQGGLPLL IPMSEVAGRM STQEGARFLE KPQGGRGILL GGVPGVKPAK VLVLGGGIVG 190 200 210 220 230 240 TNAALMAAGL GADVTICDIS LPRLRQLSEF MPKNVKTLFS SSHNIEKELP TTDLIIGAVL 250 260 270 280 290 300 IPGAKAPHLI TRPMLKLMKK GTVLVDVAID QGGCFETSHP TTHAEPIYEV DGIIHYCVAN 310 320 330 340 350 360 IPGAVPCTST LALTNATLPY AIRLADLGWE KACENDPGLK NGLNIVNGKI VFPAVAEAFG WKI

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR41418.1.
RefSeq	YP_001301040.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6L6V4.
SMR	A6L6V4. Positions 1-360.
ModBase	Search...
Protein-protein interaction databases
STRING	A6L6V4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5304766.
GenomeReviews	Gene locus BVU_3807 in contig CP000139_GR.
KEGG	bvu:BVU_3807.
NMPDR	fig|435590.6.peg.3529.
PATRIC	21072690. VBIBacVul85104_3915.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0686.
HOGENOM	HBG289735.
OMA	VAHGHEV.
ProtClustDB	CLSK822772.
Family and domain databases
InterPro	IPR008143. Ala_DH/PNT_CS2. IPR008141. Ala_DH/Pyr_transHydgase. IPR007886. AlaDH/PNT_N. IPR007698. AlaDH/PNT_NAD(H)-bd. [Graphical view]
KO	K00259.
PANTHER	PTHR10160:SF3. PTHR10160:SF3. 1 hit.
Pfam	PF01262. AlaDh_PNT_C. 1 hit. PF05222. AlaDh_PNT_N. 1 hit. [Graphical view]
PIRSF	PIRSF000183. Alanine_dh. 1 hit.
SMART	SM01002. AlaDh_PNT_C. 1 hit. SM01003. AlaDh_PNT_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR00518. AlaDH. 1 hit.
PROSITE	PS00837. ALADH_PNT_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6L6V4_BACV8

Accession

Primary (citable) accession number: A6L6V4

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)