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A6L4U5

- UXAB_BACV8

UniProt

A6L4U5 - UXAB_BACV8

Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (24 Jul 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 2912NADUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. tagaturonate reductase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciBVUL435590:GH96-3067-MONOMER.
    UniPathwayiUPA00246.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
    Alternative name(s):
    Tagaturonate dehydrogenaseUniRule annotation
    Tagaturonate reductaseUniRule annotation
    Gene namesi
    Name:uxaBUniRule annotation
    Ordered Locus Names:BVU_3075
    OrganismiBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154)
    Taxonomic identifieri435590 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
    ProteomesiUP000002861: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 479479Altronate oxidoreductasePRO_1000044700Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi435590.BVU_3075.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0246.
    HOGENOMiHOG000029586.
    KOiK00041.
    OMAiSKFKVRV.
    OrthoDBiEOG6CVVB8.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPiMF_00670. Altron_oxidoreduct.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF48179. SSF48179. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A6L4U5-1 [UniParc]FASTAAdd to Basket

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    MKALNKETAA KTQRPERIIQ FGEGNFLRAF VDWIIYNMNE KTDFNSSVVV    50
    VQPIEKGMVD MLNAQDCLYH VNLQGLDKGQ VVNSLTKIDV ISRALNPYSQ 100
    NDEFMKLAEQ PEMRFVISNT TEAGIAFDPA CKLDDAPASS YPGKLTQLLY 150
    HRYKTFNGDK SKGLIIFPCE LIFLNGHKLK ETIYQYIDLW NLGEDFKQWF 200
    EEACGVYATL VDRIVPGFPR KDIAAIKEKL QYDDNLVVQA EIFHLWVIEA 250
    PQEVAKEFPA DKAGLNVLFV PSEAPYHERK VTLLNGPHTV LSPVAYLSGI 300
    NIVREACEHE VVGKYIHKVM FDELMETLNL PKEELKKFAE DVLERFNNPF 350
    VDHQVTSIML NSFPKYETRD LPGLKVYLER KGELPKGLVL GLAAIITYYK 400
    GGVRADGAEI VPNDAPEIMN LLKELWATGC TQKVAEGVLA AESIWGENLN 450
    NIPGLTAAVK ADLDSIQEKG MLETVKGIL 479
    Length:479
    Mass (Da):53,904
    Last modified:July 24, 2007 - v1
    Checksum:i3D62C2A140C6764E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000139 Genomic DNA. Translation: ABR40709.1.
    RefSeqiYP_001300331.1. NC_009614.1.

    Genome annotation databases

    EnsemblBacteriaiABR40709; ABR40709; BVU_3075.
    GeneIDi5304036.
    KEGGibvu:BVU_3075.
    PATRICi21071168. VBIBacVul85104_3172.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000139 Genomic DNA. Translation: ABR40709.1 .
    RefSeqi YP_001300331.1. NC_009614.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 435590.BVU_3075.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABR40709 ; ABR40709 ; BVU_3075 .
    GeneIDi 5304036.
    KEGGi bvu:BVU_3075.
    PATRICi 21071168. VBIBacVul85104_3172.

    Phylogenomic databases

    eggNOGi COG0246.
    HOGENOMi HOG000029586.
    KOi K00041.
    OMAi SKFKVRV.
    OrthoDBi EOG6CVVB8.

    Enzyme and pathway databases

    UniPathwayi UPA00246 .
    BioCyci BVUL435590:GH96-3067-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    HAMAPi MF_00670. Altron_oxidoreduct.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR023668. Altronate_OxRdtase.
    IPR013328. DH_multihelical.
    IPR013118. Mannitol_DH_C.
    IPR013131. Mannitol_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF01232. Mannitol_dh. 1 hit.
    PF08125. Mannitol_dh_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48179. SSF48179. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 8482 / DSM 1447 / NCTC 11154.

    Entry informationi

    Entry nameiUXAB_BACV8
    AccessioniPrimary (citable) accession number: A6L4U5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3