A6L1M7 (A6L1M7_BACV8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycosyltransferase family 19, candidate lipid-alpha-disaccharide synthase EMBL ABR39591.1

Gene names

Ordered Locus Names:

BVU_1917

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	379 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6L1M7 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 656F22C9ED2E1BAD	FASTA	379	43,095
	10 20 30 40 50 60 MKYYLIVGEA SGDLHASNLM RALIQEDPEA EFRFFGGDLM TAVGGTRVKH YKELAYMGFI 70 80 90 100 110 120 PVLLHLRTIF RNMKECKQDI VRWTPDVVIL VDYPGFNLKI AEFIKKQTKI PVYYYISPKI 130 140 150 160 170 180 WAWKEYRIKN IKRDVDELFS ILPFEVEFFA GHQYPVHYVG NPCVDAVDAY CKEHPDGFPE 190 200 210 220 230 240 FVADNGLSEK PVIALLAGSR KQEIKDNLPM MLEAAAPFTK DYQLVLAGAP GMDPAYYSDY 250 260 270 280 290 300 INPNVPVKII FGQTYRLLQH AQAALVTSGT ATLETALFRV PQVVCYYTPV GKFIAFLRRH 310 320 330 340 350 360 ILKVKYISLV NLVADKEVVR ELVADTMTVD NVRSELESLL YNKVYRNKVL EEYDRIIQIL 370 GPAGASGTAA REMVALLKK

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR39591.1.
RefSeq	YP_001299213.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6L1M7.
ModBase	Search...
Protein-protein interaction databases
STRING	A6L1M7.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5302883.
GenomeReviews	Gene locus BVU_1917 in contig CP000139_GR.
KEGG	bvu:BVU_1917.
NMPDR	fig|435590.6.peg.1803.
PATRIC	21068734. VBIBacVul85104_1985.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0763.
HOGENOM	HBG584837.
OMA	AEFAFIC.
ProtClustDB	CLSK2391382.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6L1M7_BACV8

Accession

Primary (citable) accession number: A6L1M7

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)