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A6L011 (AROK_BACV8) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Shikimate kinase

Short name=SK
EC=2.7.1.71
Gene names
Name:aroK
Ordered Locus Names:BVU_1336
OrganismBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]
Taxonomic identifier435590 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length175 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate By similarity. HAMAP MF_00109

Catalytic activity

ATP + shikimate = ADP + shikimate 3-phosphate. HAMAP MF_00109

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP MF_00109

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7. HAMAP MF_00109

Subunit structure

Monomer By similarity. HAMAP MF_00109

Subcellular location

Cytoplasm By similarity HAMAP MF_00109.

Sequence similarities

Belongs to the shikimate kinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Magnesium
Metal-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

shikimate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 175175Shikimate kinase HAMAP MF_00109
PRO_1000094374

Regions

Nucleotide binding11 – 166ATP By similarity

Sites

Metal binding151Magnesium By similarity
Binding site331Substrate By similarity
Binding site571Substrate By similarity
Binding site791Substrate; via amide nitrogen By similarity
Binding site1181ATP By similarity
Binding site1401Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
A6L011 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: F71E59F6FEE61632

FASTA17520,453
        10         20         30         40         50         60 
MTRIFLIGYM GAGKTTLGKA FAREMSLNFI DLDWFIEERF HKTVQQLFLE RGEDGFRELE 

        70         80         90        100        110        120 
RKMLHEVAEF EDVVVSTGGG TPCFFDNMEY MNDCGDTVFL DVEPAVLFRR LRVAKQQRPL 

       130        140        150        160        170 
LANKSDEELM DFICEALQKR HPFYSKAKHL FKADELEDKR QIQASVDSLR KKLNK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000139 Genomic DNA. Translation: ABR39025.1.
RefSeqYP_001298647.1. NC_009614.1.

3D structure databases

ProteinModelPortalA6L011.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6L011.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5302302.
GenomeReviewsGene locus BVU_1336 in contig CP000139_GR.
KEGGbvu:BVU_1336.
NMPDRfig|435590.6.peg.1258.
PATRIC21067512. VBIBacVul85104_1389.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0703.
HOGENOMHBG335815.
OMAMIISERV.
ProtClustDBPRK13949.

Family and domain databases

HAMAPMF_00109. Shikimate_kinase.
[Tree]
InterProIPR000623. Shikimate_kinase.
[Graphical view]
KOK00891.
PfamPF01202. SKI. 1 hit.
[Graphical view]
PRINTSPR01100. SHIKIMTKNASE.
PROSITEPS01128. SHIKIMATE_KINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROK_BACV8
AccessionPrimary (citable) accession number: A6L011
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: July 24, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families