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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei48NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:BVU_1172
OrganismiBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Taxonomic identifieri435590 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000002861 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000845501 – 235tRNA pseudouridine synthase BAdd BLAST235

Interactioni

Protein-protein interaction databases

STRINGi435590.BVU_1172

Structurei

3D structure databases

ProteinModelPortaliA6KZJ9
SMRiA6KZJ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A6KZJ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFKEGEVLY FDKPLKWTSF AVVNKIRYHI CRKLGVKKIK VGHAGTLDPL
60 70 80 90 100
ATGVMIICTG KATKRIEEFQ YHTKEYIATL QLGATTPSFD LEKEIDATYP
110 120 130 140 150
TEHITRELVE EALQRFIGRI EQIPPVFSAC KVDGKRAYDL ARKGEDVELK
160 170 180 190 200
AKTLIIDEIE LLECNLPEIK IRVVCSKGTY IRALARDIGE ALNSGAHLTG
210 220 230
LIRTRVGDVR LEDCLSVESF PEWLDQQEIE EVINE
Length:235
Mass (Da):26,652
Last modified:July 24, 2007 - v1
Checksum:i8EC8AAB3A0F84C91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000139 Genomic DNA Translation: ABR38863.1
RefSeqiWP_005844015.1, NC_009614.1

Genome annotation databases

EnsemblBacteriaiABR38863; ABR38863; BVU_1172
GeneIDi5302138
KEGGibvu:BVU_1172

Similar proteinsi

Entry informationi

Entry nameiTRUB_BACV8
AccessioniPrimary (citable) accession number: A6KZJ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 24, 2007
Last modified: March 28, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health