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A6KZA8 (SYR_BACV8) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:BVU_1081
OrganismBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]
Taxonomic identifier435590 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length606 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 606606Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000017988

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A6KZA8 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 46C8E5D9092A1F0B

FASTA60667,998
        10         20         30         40         50         60 
MNIEEKLTTS IISAIKTLYG QDVPGKMVQL QKTKKEFEGH LTLVVFPFLK MSKKGPEQTA 

        70         80         90        100        110        120 
QEIGGYLKEH APELVSAYNA VKGFLNLTIA SDCWIELLNS IQAAPEYGIE KATENSPLVM 

       130        140        150        160        170        180 
IEYSSPNTNK PLHLGHVRNN LLGNALANVM AANGNKVVKT NIVNDRGIHI CKSMLAWLKY 

       190        200        210        220        230        240 
GNGETPESSG KKGDHLIGDY YVAFDKHYKA EVKELTAQYQ AEGLNEEEAK AKAEANSPLM 

       250        260        270        280        290        300 
LEAREMLRKW EANDPEIRAL WKKMNDWVYA GFDETYKMMG VSFDKIYYES NTYLEGKEKV 

       310        320        330        340        350        360 
MEGLEKGFFY RKEDNSVWAD LTAEGLDHKL LLRGDGTSVY MTQDIGTAKL RFQDYPINKM 

       370        380        390        400        410        420 
IYVVGNEQNY HFQVLSILLD KLGFEWGKGL VHFSYGMVEL PEGKMKSREG TVVDADDLME 

       430        440        450        460        470        480 
AMIETAKETS AELGKLDGLT QEEADNIARI VGLGALKYFI LKVDARKNMT FNPKESIDFN 

       490        500        510        520        530        540 
GNTGPFIQYT YARIQSVLRK AAEAGIVIPE IIPAGLELSA KEEGLIQMLA DFKSVVKQAG 

       550        560        570        580        590        600 
SDYNPSIIAN YAYDLVKEYN QFYHDFSILR EENEALKVFR LALSANVGKI VKTAMGLLGI 


EVPERM 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000139 Genomic DNA. Translation: ABR38772.1.
RefSeqYP_001298394.1. NC_009614.1.

3D structure databases

ProteinModelPortalA6KZA8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING435590.BVU_1081.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABR38772; ABR38772; BVU_1081.
GeneID5302047.
KEGGbvu:BVU_1081.
PATRIC21066968. VBIBacVul85104_1119.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMADGTAVYM.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycBVUL435590:GH96-1078-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_BACV8
AccessionPrimary (citable) accession number: A6KZA8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries