A6KYK6 (RL1_BACV8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L1

Gene names

Name:	rplA
Ordered Locus Names:	BVU_0816

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release By similarity. HAMAP MF_01318_B Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA By similarity. HAMAP MF_01318_B
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L1P family.

Ontologies

Keywords
Biological process	Translation regulation
Ligand	RNA-binding rRNA-binding tRNA-binding
Molecular function	Repressor Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW translation Inferred from electronic annotation. Source: InterPro
Cellular component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	50S ribosomal protein L1 HAMAP MF_01318_B		PRO_0000307961

Sequences

	Sequence		Length	Mass (Da)
	A6KYK6 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 27200FC6BDFB6071	FASTA	232	24,934
	10 20 30 40 50 60 MGKLTKNQKL AAEKIEAGKA YSLKEAAQLV KDITFSKFDA SLDIDVRLGV DPRKANQMVR 70 80 90 100 110 120 GVVSLPHGTG KQVRVLVLCT PDAEAAAKEA GADYVGLDEY IEKIKGGWTD IDVIITMPSI 130 140 150 160 170 180 MGKIGALGRV LGPRGLMPNP KSGTVTMDVA KAVKEVKQGK IDFKVDKSGI VHTSIGKVSF 190 200 210 220 230 TADQIRDNAK EFIATIIKLK PSSAKGTYIK SIYLSSTMSK GIKIDPKTVE EN

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8482 / DSM 1447 / NCTC 11154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR38520.1.
RefSeq	YP_001298142.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6KYK6.
ModBase	Search...
Protein-protein interaction databases
STRING	A6KYK6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5301783.
GenomeReviews	Gene locus BVU_0816 in contig CP000139_GR.
KEGG	bvu:BVU_0816.
NMPDR	fig|435590.6.peg.783.
PATRIC	21066402. VBIBacVul85104_0847.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0081.
HOGENOM	HBG297400.
OMA	FEDYIEK.
ProtClustDB	PRK05424.
Family and domain databases
HAMAP	MF_01318_B. Ribosomal_L1_B. [Tree]
InterPro	IPR005878. Ribosom_L1_bac-type. IPR002143. Ribosomal_L1. IPR016094. Ribosomal_L1_2-a/b-sand. IPR016095. Ribosomal_L1_3-a/b-sand. IPR023673. Ribosomal_L1_CS. IPR023674. Ribosomal_L1_SF. [Graphical view]
Gene3D	G3DSA:3.30.190.20. Ribosomal_L1_2-a/b-sand. 2 hits. G3DSA:3.40.50.790. Ribosomal_L1_3-a/b-sand. 1 hit.
KO	K02863.
Pfam	PF00687. Ribosomal_L1. 1 hit. [Graphical view]
PIRSF	PIRSF002155. Ribosomal_L1. 1 hit.
SUPFAM	SSF56808. Ribosomal_L1. 1 hit.
TIGRFAMs	TIGR01169. RplA_bact. 1 hit.
PROSITE	PS01199. RIBOSOMAL_L1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL1_BACV8

Accession

Primary (citable) accession number: A6KYK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program