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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:BVU_0813
OrganismiBacteroides vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / NBRC 14291 / NCTC 11154)
Taxonomic identifieri435590 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000002861 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003002811 – 1270DNA-directed RNA polymerase subunit betaAdd BLAST1270

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi435590.BVU_0813.

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218612.
KOiK03043.
OMAiYFNPKRY.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 4 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A6KYK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSNTENQRV NFASIKNPMK YPDFLEVQLK SFQDFLQLDT PPEKRKNDGL
60 70 80 90 100
YKVFAENFPI ADTRNNFVLE FLDYYIDPPH YSIDECLERG LTYSVPLKAK
110 120 130 140 150
LKLYCTDPDH EDFDTVIQDV YLGPIPYMTP KGTFVINGAE RVVVSQLHRS
160 170 180 190 200
PGVFFGQSVH ANGTKLYSAR IIPFKGSWIE FATDINNVMY AYIDRKKKLP
210 220 230 240 250
VTTLLRAVGF ENDKDILEIF NLAEDVKVNK TNLKKVVGRK LAARVLKTWT
260 270 280 290 300
EDFVDEDTGE VVSIERNEVI IDRETVIEED HIDEIIDSGV QNILVHKEEA
310 320 330 340 350
NSSDYSIIFN TLQKDPSNSE KEAVLYIYRQ LRNADPADDA SAREVINNLF
360 370 380 390 400
FSEKRYDLGE VGRYRINKKL GLTTDMDVKV LTKQDIIEII KYLIELINSK
410 420 430 440 450
ADVDDIDHLS NRRVRTVGEQ LSNQFAIGLA RMSRTIRERM NVRDNEVFTP
460 470 480 490 500
IDLINAKTIS SVINSFFGTN ALSQFMDQTN PLAEITHKRR LSALGPGGLS
510 520 530 540 550
RERAGFEVRD VHYTHYGRLC PIETPEGPNI GLISSLCVYA KINELGFIST
560 570 580 590 600
PYRKVADGKV DISDEGIEYL TAEEEEDKII AQGNAPLDDE GKFVREKVKA
610 620 630 640 650
RRDADYPVVT PDQVELMDVS PQQIASIAAS LIPFLEHDDA NRALMGSNMM
660 670 680 690 700
RQAVPLLRTE APIVGTGIEK QLVEDSRTQI AAEGDGVVEY VDATTIRILY
710 720 730 740 750
DRNEDEEFVS FEPALKEYRI PKFRKTNQSM TIDLRPTCDK GQRVKKGDIL
760 770 780 790 800
TEGYSTQGGE LALGKNLLVA YMPWKGYNYE DAIVLNERVV REDLLTSVHV
810 820 830 840 850
DEYILEVRET KRGMEELTSD IPNVSEEATK DLDENGIVRV GARIEPGDIL
860 870 880 890 900
IGKITPKGES DPSPEEKLLR AIFGDKAGDV KDASLKASPS LRGVVIDKKL
910 920 930 940 950
FSRVIKSRSE KNADKAILPK LNDEFEEKAA KLKDILIEKL LVLTNGKVSQ
960 970 980 990 1000
GVKDYLGTEV IAKGAKFTKR DLESLDYTII QLSKWTADAH KNDMIRDLVM
1010 1020 1030 1040 1050
NYLKKYKELD AELKRKKFAI TIGDELPAGI IQMAKVYIAK KRKIGVGDKM
1060 1070 1080 1090 1100
AGRHGNKGIV SRVVRQEDMP FLADGTPVDI VLNPLGVPSR MNIGQIFEAV
1110 1120 1130 1140 1150
LGRAGKELGV KFATPIFDGA SMDDLNEWTD KAGLPRYCKT YLCDGGTGER
1160 1170 1180 1190 1200
FDQPATVGVT YMLKLGHMVE DKMHARSIGP YSLITQQPLG GKAQFGGQRF
1210 1220 1230 1240 1250
GEMEVWALEA FGAAHILQEI LTIKSDDVVG RSKAYEAIVK GEPMPTPGIP
1260 1270
ESLNVLLHEL RGLGLSINLE
Length:1,270
Mass (Da):142,485
Last modified:July 24, 2007 - v1
Checksum:iB08E5C27D60D76F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000139 Genomic DNA. Translation: ABR38517.1.
RefSeqiWP_005844834.1. NC_009614.1.

Genome annotation databases

EnsemblBacteriaiABR38517; ABR38517; BVU_0813.
GeneIDi5301780.
KEGGibvu:BVU_0813.
PATRICi21066396. VBIBacVul85104_0844.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000139 Genomic DNA. Translation: ABR38517.1.
RefSeqiWP_005844834.1. NC_009614.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi435590.BVU_0813.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR38517; ABR38517; BVU_0813.
GeneIDi5301780.
KEGGibvu:BVU_0813.
PATRICi21066396. VBIBacVul85104_0844.

Phylogenomic databases

eggNOGiENOG4108IIJ. Bacteria.
COG0085. LUCA.
HOGENOMiHOG000218612.
KOiK03043.
OMAiYFNPKRY.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 2 hits.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 4 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB_BACV8
AccessioniPrimary (citable) accession number: A6KYK3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: July 24, 2007
Last modified: November 2, 2016
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.