A6KYH1 (RS4_BACV8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	BVU_0781

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP MF_01306_B		PRO_0000322268
Regions
	Domain	92 – 155	64	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	A6KYH1 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: B2507C5E549437C2	FASTA	201	22,539
	10 20 30 40 50 60 MARYTGPKSR IARKFGEGIF GADKVLSKKN YPPGQHGNNR RRKTSEYGVM LAEKQKAKYT 70 80 90 100 110 120 YGVLEKQFRN LFEKAASANG ITGEILLQSL EARLDNVVFR LGIAPTRAAA RQLVSHKHIT 130 140 150 160 170 180 VDGKVVNIPS FSVKPGQIVG VRERSKSLEV IANSLAGFNH SKYPWLEWDE SSKVGKLLHI 190 200 PERADIPENI KEHLIVELYS K

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 8482 / DSM 1447 / NCTC 11154.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR38485.1.
RefSeq	YP_001298107.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6KYH1.
SMR	A6KYH1. Positions 43-201.
ModBase	Search...
Protein-protein interaction databases
STRING	A6KYH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5301748.
GenomeReviews	Gene locus BVU_0781 in contig CP000139_GR.
KEGG	bvu:BVU_0781.
NMPDR	fig|435590.6.peg.747.
PATRIC	21066328. VBIBacVul85104_0810.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0522.
HOGENOM	HBG285740.
OMA	QLVVELY.
ProtClustDB	PRK05327.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_BACV8

Accession

Primary (citable) accession number: A6KYH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 26, 2008
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program