A6KWU3 (A6KWU3_BACV8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Beta-galactosidase PIRNR PIRNR001084
Short name=Beta-gal PIRNR PIRNR001084
EC=3.2.1.23 PIRNR PIRNR001084

Gene names

Ordered Locus Names:

BVU_0179

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. PIRNR PIRNR001084
Sequence similarities	Belongs to the glycosyl hydrolase 42 family. PIRNR PIRNR001084

Ontologies

Keywords
Molecular function	Glycosidase PIRNR PIRNR001084 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular function	beta-galactosidase activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	172	1	Proton donor By similarity PIRSR PIRSR001084-1
	Active site	334	1	Nucleophile By similarity PIRSR PIRSR001084-1
	Binding site	133	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	171	1	Substrate By similarity PIRSR PIRSR001084-2
	Binding site	342	1	Substrate By similarity PIRSR PIRSR001084-2

Sequences

	Sequence		Length	Mass (Da)
	A6KWU3 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: F9A01D0A6B087A54	FASTA	692	79,587
	10 20 30 40 50 60 MKKRFVTVLL ACSLAGGLFA QQPWFKDKDL TLTGAYYYPE HWDESQWERD FKQMHDLGFE 70 80 90 100 110 120 FTHFAEFAWA QLEPEEGKYD FAWLDKAVAL AAKYDLKVIM CTSTATPPVW LSRKYPEILI 130 140 150 160 170 180 KNENGTVLDH GARQHASFAS PVYRELAYKM IEKLAQHYGN DSRIIGWQLD NEPAVQFDYN 190 200 210 220 230 240 PKAELAFRDF LREKYHHDIK ALNDAWGTAF WSEVYSSFDE ITLPKTAQMF MNHHQILDYR 250 260 270 280 290 300 RFAASQTNDF LNEQCLLIKK YAKNQWVTTN YIPNYEEGHI GGSPTLDFQS YTRYMVYGDN 310 320 330 340 350 360 EGIGRRGYRV GNPLRIAFAN DFFRPIQGTY GVMELQPGQV NWGSINPQPL PGAIRLWMWS 370 380 390 400 410 420 VFAGGGDFIC TYRYRQPLYG TEQYHYGIVG TDGTTVTPGG REYEQFMKEI RQLRGQVAAR 430 440 450 460 470 480 EVKPADYLAR RTAILFNHEN SWSIERQKQN RTWNTLGHIE KYYRTLKSFG APVDFINESK 490 500 510 520 530 540 EFSSYPVIIA PAYQLADKAL VDRWTDYVKK GGNLVLTCRT AQKDRHGRLP EAPFGSMINE 550 560 570 580 590 600 LTGNEMEFYD LLLLEEPGKL RMDGKEYTWN TWGEILKSGK DSQVWATYTQ EFYEGKPAVT 610 620 630 640 650 660 TRKLGKGTVT YVGVDSTDGL LEKDILKKLY AQLNIPVMDL PYGVTLEYRN GMGIVLNYTD 670 680 690 KPYKFVLPSG AKVLIGEPVI PTAGVLVFSI TD

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR37907.1.
RefSeq	YP_001297529.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6KWU3.
ModBase	Search...
Protein-protein interaction databases
STRING	A6KWU3.
Protein family/group databases
CAZy	GH42. Glycoside Hydrolase Family 42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5301149.
GenomeReviews	Gene locus BVU_0179 in contig CP000139_GR.
KEGG	bvu:BVU_0179.
NMPDR	fig|435590.6.peg.176.
PATRIC	21065046. VBIBacVul85104_0187.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1874.
HOGENOM	HBG346187.
OMA	HASFASP.
ProtClustDB	CLSK823809.
Family and domain databases
InterPro	IPR013738. Beta_galactosidase_Trimer. IPR013780. Glyco_hydro_13_b. IPR003476. Glyco_hydro_42. IPR013529. Glyco_hydro_42_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
Gene3D	G3DSA:2.60.40.1180. Glyco_hydro_13_b. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
KO	K12308.
Pfam	PF02449. Glyco_hydro_42. 1 hit. PF08532. Glyco_hydro_42M. 1 hit. [Graphical view]
PIRSF	PIRSF001084. B-galactosidase. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6KWU3_BACV8

Accession

Primary (citable) accession number: A6KWU3

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)