A6KWL5 (A6KWL5_BACV8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase EMBL ABR37829.1

Gene names

Ordered Locus Names:

BVU_0099

Organism

Bacteroides vulgatus (strain ATCC 8482 / DSM 1447 / NCTC 11154) [Complete proteome] [HAMAP]

Taxonomic identifier

435590 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	255 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS010137
Catalytic activity	(R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetylglucosamine = [acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine. SAAS SAAS010137
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6. SAAS SAAS010137
Subunit structure	Homotrimer By similarity. SAAS SAAS010137
Subcellular location	Cytoplasm By similarity SAAS SAAS010137.

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS010137 Lipid synthesis
Cellular component	Cytoplasm SAAS SAAS010137
Domain	Repeat SAAS SAAS010137
Molecular function	Acyltransferase SAAS SAAS010137 EMBL ABR37829.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A6KWL5 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 7F9C652C6EBBBF59	FASTA	255	27,739
	10 20 30 40 50 60 MISPLAYIHP EAKIGENVEI GPFVFIDKNV VIGDNNTIMP NANILYGSRI GNGNTIFPGA 70 80 90 100 110 120 VIGAIPQDLK FRGEETTAEI GDNNTIRENV TINRGTAAKG KTIVGSNNLL MEGVHVAHDA 130 140 150 160 170 180 IIGSGCIIGN ATKMAGEIII DDNAIISGAV LMHQFCRVGG YVMVQGGSRF SKDIPPYIIA 190 200 210 220 230 240 GREPIAYAGI NIVGLRRRGF SNELIENIHN TYRIIYQNGM NVTDALEQVR KEIPMSKEIE 250 YIISFIENSQ RGIIR

References

[1]

"Evolution of symbiotic bacteria in the distal human intestine." Xu J., Mahowald M.A., Ley R.E., Lozupone C.A., Hamady M., Martens E.C., Henrissat B., Coutinho P.M., Minx P., Latreille P., Cordum H., Van Brunt A., Kim K., Fulton R.S., Fulton L.A., Clifton S.W., Wilson R.K., Knight R.D., Gordon J.I. PLoS Biol. 5:1574-1586(2007) [PubMed: 17579514] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000139 Genomic DNA. Translation: ABR37829.1.
RefSeq	YP_001297451.1. NC_009614.1.
3D structure databases
ProteinModelPortal	A6KWL5.
ModBase	Search...
Protein-protein interaction databases
STRING	A6KWL5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5301069.
GenomeReviews	Gene locus BVU_0099 in contig CP000139_GR.
KEGG	bvu:BVU_0099.
NMPDR	fig|435590.6.peg.98.
PATRIC	21064873. VBIBacVul85104_0103.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1043.
HOGENOM	HBG659295.
OMA	REFCTFN.
ProtClustDB	PRK05289.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR010137. Lipid_A_lpxA. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00677.
Pfam	PF00132. Hexapep. 3 hits. [Graphical view]
PIRSF	PIRSF000456. UDP-GlcNAc_acltr. 1 hit.
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01852. Lipid_A_lpxA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6KWL5_BACV8

Accession

Primary (citable) accession number: A6KWL5

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)