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Protein

UDP-glucuronosyltransferase

Gene

UGT2A3

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:UGT2A3Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei494 – 517HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_500512170324 – 530UDP-glucuronosyltransferaseUniRule annotationAdd BLAST507

Proteomic databases

PaxDbiA6H7H4.

Structurei

3D structure databases

ProteinModelPortaliA6H7H4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini357 – 400UDPGTInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
HOGENOMiHOG000220831.
HOVERGENiHBG004033.
KOiK00699.

Family and domain databases

InterProiView protein in InterPro
IPR002213. UDP_glucos_trans.
IPR035595. UDP_glycos_trans_CS.
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiView protein in Pfam
PF00201. UDPGT. 1 hit.
PROSITEiView protein in PROSITE
PS00375. UDPGT. 1 hit.

Sequencei

Sequence statusi: Complete.

A6H7H4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSKKWVSAI LLLQLCYTGC GFCEKVLVWP CDMSHWLNLK VILEKLMERG
60 70 80 90 100
HEVTVLVSSQ NFLIENNKPS TLNFEMFSVP QDKETAEDGL NEFLNLSVNV
110 120 130 140 150
MPTLSPWQSA KKLQDFFLQI SADLKLVCES VVYNQTIMKK LQDTNYNVMV
160 170 180 190 200
IDPVMPCGEL IAETLGIPFV YTLRLSLGST MERYCGQIPS PPSYVPVVMA
210 220 230 240 250
ALPDKMTFLQ RVKNLMFTIF FDFWLQQYDS QLWDQFYSEV LGRPTTLCET
260 270 280 290 300
MGKAEIWLIR TYWDFEFPRP YLPNFEFVGG LHCKPAKPLP KEMEEFVQSS
310 320 330 340 350
GEDGIVVFSL GSMVKNLTEE KANRIASALA QIPQKVLWRY KGKKPATLGA
360 370 380 390 400
NTRLYDWIPQ NDLLGHPKAK AFITHGGTNG IYEAIYHGVP MVGVPMFADQ
410 420 430 440 450
PDNIAHMKAK GAAVEVNINT VTSADLLNAL RTVINEPSYK ENAMRLKRIH
460 470 480 490 500
HDQPVKPLDR AVFWIEFVMR HKGAKHLRPA AHNLTWYQYH SLDVIGFLLA
510 520 530
CVATAVFLVT RCCLFSCRKF GKTGKKKKRE
Length:530
Mass (Da):60,405
Last modified:July 24, 2007 - v1
Checksum:i01AEA620C60DDD35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC146247 mRNA. Translation: AAI46248.1.
RefSeqiNP_001092414.1. NM_001098944.1.
UniGeneiBt.42075.

Genome annotation databases

GeneIDi511743.
KEGGibta:511743.

Similar proteinsi

Entry informationi

Entry nameiA6H7H4_BOVIN
AccessioniPrimary (citable) accession number: A6H7H4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: October 25, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)