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Protein

Transmembrane protein 70, mitochondrial

Gene

TMEM70

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in biogenesis of mitochondrial ATP synthase.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 70, mitochondrial
Gene namesi
Name:TMEM70
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 14

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei113 – 133HelicalSequence analysisAdd BLAST21
Transmembranei137 – 157HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 78MitochondrionSequence analysisAdd BLAST78
ChainiPRO_000036154679 – 254Transmembrane protein 70, mitochondrialAdd BLAST176

Proteomic databases

PaxDbiA6H773.

Expressioni

Gene expression databases

BgeeiENSBTAG00000012920.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017169.

Family & Domainsi

Sequence similaritiesi

Belongs to the TMEM70 family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4478. Eukaryota.
ENOG4111HEE. LUCA.
GeneTreeiENSGT00390000018710.
HOGENOMiHOG000045718.
HOVERGENiHBG073273.
InParanoidiA6H773.
KOiK17966.
OMAiRTVFGVK.
OrthoDBiEOG091G184V.
TreeFamiTF314656.

Family and domain databases

InterProiIPR009724. TMEM70.
[Graphical view]
PANTHERiPTHR13281. PTHR13281. 1 hit.
PfamiPF06979. TMEM70. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A6H773-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFLALGGPW AAGLRLSGKR TALWASSALR DPRAAVSRAA SCRGSSGRVG
60 70 80 90 100
GTGLSAAAPV LRRVRAQIPV CWERGVRCSH TQLDKSEDGR LIYTGNLART
110 120 130 140 150
VFGVKCFSYS TSLISLAFLP YIFAQNNVIF GSLPLQILFY GTIGSFTVIT
160 170 180 190 200
PALLHFLTKG YVIRLYHEAR TDTYKAITYS VVLSEKSTVF HQNDVKIPNS
210 220 230 240 250
THVFTTFYAK TKSLLVNPAL FPNPEDYNHL MGYDKPFTFD LEEASEKKQL

KEEK
Length:254
Mass (Da):28,139
Last modified:July 24, 2007 - v1
Checksum:i96E80DA818A25DD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC146138 mRNA. Translation: AAI46139.1.
RefSeqiNP_001092596.1. NM_001099126.2.
UniGeneiBt.56694.

Genome annotation databases

EnsembliENSBTAT00000017169; ENSBTAP00000017169; ENSBTAG00000012920.
GeneIDi613774.
KEGGibta:613774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC146138 mRNA. Translation: AAI46139.1.
RefSeqiNP_001092596.1. NM_001099126.2.
UniGeneiBt.56694.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017169.

Proteomic databases

PaxDbiA6H773.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000017169; ENSBTAP00000017169; ENSBTAG00000012920.
GeneIDi613774.
KEGGibta:613774.

Organism-specific databases

CTDi54968.

Phylogenomic databases

eggNOGiKOG4478. Eukaryota.
ENOG4111HEE. LUCA.
GeneTreeiENSGT00390000018710.
HOGENOMiHOG000045718.
HOVERGENiHBG073273.
InParanoidiA6H773.
KOiK17966.
OMAiRTVFGVK.
OrthoDBiEOG091G184V.
TreeFamiTF314656.

Gene expression databases

BgeeiENSBTAG00000012920.

Family and domain databases

InterProiIPR009724. TMEM70.
[Graphical view]
PANTHERiPTHR13281. PTHR13281. 1 hit.
PfamiPF06979. TMEM70. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTMM70_BOVIN
AccessioniPrimary (citable) accession number: A6H773
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: July 24, 2007
Last modified: September 7, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.