Reviewed,
UniProtKB/Swiss-Prot A6H730 (PPAP_BOVIN)
Last modified
November 3, 2009.
Version 16.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Prostatic acid phosphatase EC=3.1.3.2 | ||
| Gene names |
| ||
| Organism | Bos taurus (Bovine) | ||
| Taxonomic identifier | 9913 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Protein attributes
| Sequence length | 387 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | A phosphate monoester + H2O = an alcohol + phosphate. |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Secreted By similarity. |
| Sequence similarities | Belongs to the histidine acid phosphatase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Molecular function | Hydrolase |
| PTM | Disulfide bond Glycoprotein |
| Gene Ontology (GO) | |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | acid phosphatase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 34 | 34 | Potential | ||||||||
| Chain | 35 – 387 | 353 | Prostatic acid phosphatase | PRO_0000356292 | |||||||
Sites | |||||||||||
| Active site | 46 | 1 | Nucleophile By similarity | ||||||||
| Active site | 292 | 1 | Proton donor By similarity | ||||||||
Amino acid modifications | |||||||||||
| Glycosylation | 96 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 222 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 335 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Disulfide bond | 163 ↔ 374 | By similarity | |||||||||
| Disulfide bond | 217 ↔ 315 | By similarity | |||||||||
| Disulfide bond | 349 ↔ 353 | By similarity | |||||||||
Sequences
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References
| [1] | NIH - Mammalian Gene Collection (MGC) project Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: Hereford. Tissue: Fetal skin. |
Cross-references
Sequence databases | |
|---|---|
| BC146093 mRNA. Translation: AAI46094.1. | |
| IPI | IPI00707272. |
| RefSeq | NP_001092336.1. |
| UniGene | Bt.61011 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSBTAT00000015451; ENSBTAP00000015451; ENSBTAG00000011634; Bos taurus. [Genome view] |
| GeneID | 504700. |
| KEGG | bta:504700. |
Organism-specific databases | |
| CTD | 504700. |
Phylogenomic databases | |
| OMA | VHNFTLP. |
Family and domain databases | |
| InterPro | IPR000560. Histidine_acid_Pase. [Graphical view] |
| Pfam | PF00328. Acid_phosphat_A. 1 hit. [Graphical view] |
| PROSITE | PS00616. HIS_ACID_PHOSPHAT_1. 1 hit. PS00778. HIS_ACID_PHOSPHAT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PPAP_BOVIN | ||||||||
| Accession | Primary (citable) accession number: A6H730 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HPI (Human Proteome Initiative) | ||||||||

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