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Protein
Submitted name:

CD3 antigen epsilon polypeptide

Gene

Cd3e

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD3 antigen epsilon polypeptideImported
Submitted name:
CD3 antigen, epsilon polypeptideImported
Gene namesi
Name:Cd3eImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:88332. Cd3e.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei109 – 133HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501010326221 – 189Sequence analysisAdd BLAST169

Expressioni

Gene expression databases

BgeeiENSMUSG00000032093.
ExpressionAtlasiA6H6M1. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiA6H6M1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini35 – 83Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST49

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IYD1. Eukaryota.
ENOG41123JN. LUCA.
HOVERGENiHBG102121.
KOiK06451.
OMAiQRGQNKE.
OrthoDBiEOG091G0PKE.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015484. CD3_esu/gsu/dsu.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003598. Ig_sub2.
IPR003110. Phos_immunorcpt_sig_ITAM.
PANTHERiPTHR10570. PTHR10570. 1 hit.
PfamiView protein in Pfam
PF02189. ITAM. 1 hit.
SMARTiView protein in SMART
SM00408. IGc2. 1 hit.
SM00077. ITAM. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.
PROSITEiView protein in PROSITE
PS50835. IG_LIKE. 1 hit.
PS51055. ITAM_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A6H6M1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWNTFWGIL CLSLLAVGTC QDDAENIEYK VSISGTSVEL TCPLDSDENL
60 70 80 90 100
KWEKNGQELP QKHDKHLVLQ DFSEVEDSGY YVCYTPASNK NTYLYLKARV
110 120 130 140 150
CEYCVEVDLT AVAIIIIVDI CITLGLLMVI YYWSKNRKAK AKPVTRGTGA
160 170 180
GSRPRGQNKE RPPPVPNPDY EPIRKGQRDL YSGLNQRAV
Length:189
Mass (Da):21,393
Last modified:July 24, 2007 - v1
Checksum:i5CE92F784FA13B96
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC145926 mRNA. Translation: AAI45927.1.
BC145954 mRNA. Translation: AAI45955.1.
GU456631 mRNA. Translation: ADD13994.1.
RefSeqiNP_031674.1. NM_007648.4.
XP_006510029.1. XM_006509966.3.
UniGeneiMm.210361.

Genome annotation databases

GeneIDi12501.
KEGGimmu:12501.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA6H6M1_MOUSE
AccessioniPrimary (citable) accession number: A6H6M1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 24, 2007
Last sequence update: July 24, 2007
Last modified: July 5, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)