Ppp1r12b

Functionⁱ

GO - Molecular functionⁱ

protein kinase binding Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: MCG130490Imported Submitted name: Protein phosphatase 1 regulatory subunit 12BImported Submitted name: Protein phosphatase 1, regulatory (Inhibitor) subunit 12BImported
Gene namesⁱ	Name:Ppp1r12bImported ORF Names:mCG_130490Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:1916417. Ppp1r12b.

Subcellular locationⁱ

GO - Cellular componentⁱ

cytoplasm Source: UniProtKB-SubCell

Complete GO annotation...

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000073557.

Bgeeⁱ

ENSMUSG00000073557.

Interactionⁱ

GO - Molecular functionⁱ

protein kinase binding Source: InterPro

Complete GO annotation...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	57 – 290	ANK_REP_REGIONInterPro annotationAdd BLAST	234
Repeatⁱ	90 – 122	ANKPROSITE-ProRule annotationAdd BLAST	33
Repeatⁱ	123 – 155	ANKPROSITE-ProRule annotationAdd BLAST	33
Repeatⁱ	216 – 248	ANKPROSITE-ProRule annotationAdd BLAST	33
Repeatⁱ	249 – 281	ANKPROSITE-ProRule annotationAdd BLAST	33

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	873 – 921	Sequence analysisAdd BLAST		49
Coiled coilⁱ	926 – 983	Sequence analysisAdd BLAST		58

Keywords - Domainⁱ

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG0505. Eukaryota. COG0666. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119141.
HOGENOMⁱ	HOG000290648.
HOVERGENⁱ	HBG052561.
KEGG Orthology (KO) More...KOⁱ	K12329.
OMAⁱ	EKHEPSA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0UPK.
TreeFamⁱ	TF105543.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204. ANK. 1 hit.
Gene3Dⁱ	1.25.40.20. 3 hits.
InterProⁱ	View protein in InterPro IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR031775. PRKG1_interact.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796. Ank_2. 2 hits. PF15898. PRKG1_interact. 1 hit.
SMARTⁱ	View protein in SMART SM00248. ANK. 5 hits.
SUPFAMⁱ	SSF48403. SSF48403. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 4 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

A6H644-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAELEHLGGK RAESARARRA EQLRRWRGSL TEQEPAERQG AGRQLQTRRG 
        60         70         80         90        100
SPRVRFEDGA VFLAACSSGD TDEVKKLLAR GADINTVNVD GLTALHQACI 
       110        120        130        140        150
DENLDMVKFL VENRANVNQQ DNEGWTPLHA AASCGYLNIA EYFISHGASV 
       160        170        180        190        200
GIVNSEGEVP SDLAEEPAMK DLLLEQVKKQ GVDLEQSRKE EEQQMLQDAR 
       210        220        230        240        250
QWLNSGRIED VRQARSGATA LHVAAAKGYS EVLRLLIQAG YELNVQDHDG 
       260        270        280        290        300
WTPLHAAAHW GVKEACSILA EALCDMDIRN KLGQTPFDVA DEGLVEHLEM 
       310        320        330        340        350
LQKKQDVLRS EKETRNKLIE SDLNSKFQSG LFKNKEKMLY EEEIPKSQDT 
       360        370        380        390        400
EEENKESSSS SSEEEEGEDE VSESETEKEA DKKPEATVNH SNSEIKSRIM 
       410        420        430        440        450
EQIPAPAQNT FSASSARRLS SLFNKAEEPK DESPSSWRLG LRKTGSHNML 
       460        470        480        490        500
SEVANSREAL RDRGSSIYRS SSSPRISALL DDKDKERENK SYFSMLVPRR 
       510        520        530        540        550
LSSTSDIEEK ENRESAVNLV RSGSHTRQLW RDEAKGSETP QTIAPSTYTS 
       560        570        580        590        600
TYLKRTPYKS QADSTAEKTA DSVSSSTPLC VITNRPAPST ANGVPAATVF 
       610        620        630        640        650
SSAGTDPSVE AREKRRSYLT PVRDEEAESL RKARSRQARQ TRRSTQGVTL 
       660        670        680        690        700
TDLQEAEKTF SRSRAERQAQ EQPGEKLEDP GGLEGSTKKQ EPSAAPTKGA 
       710        720        730        740        750
GEGRSLEEEP IYHRLRYPTQ PDKPTTPVSP SASRPSLYTG SHLLRTSRAS 
       760        770        780        790        800
GPDSENSETS THATAAKEMD TSEKGEADLD DQSSNRLSVR ERRRAKDRRR 
       810        820        830        840        850
GTGINFWTND EDETDVSEEV KEALHERLSR LESGGTNPTS SDSYSDRASA 
       860        870        880        890        900
RARREAREAR LASLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE 
       910        920        930        940        950
LADIKAKLEK MAQQKQEKTS DRSSVLEVEK RERRALERKM SEMEEEMKNL 
       960        970        980        990 
HQLKQIQTLK QMNEQLQAEN RALTRVVARL SKSIESSDTQ EL

Length:992

Mass (Da):110,972

Last modified:July 24, 2007 - v1

Checksum:ⁱ33AE4339A832EE73

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC117827 Genomic DNA. No translation available. AC131591 Genomic DNA. No translation available. BC145746 mRNA. Translation: AAI45747.1. CH466520 Genomic DNA. Translation: EDL39598.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001074776.1. NM_001081307.1. XP_006529772.1. XM_006529709.3.
UniGeneⁱ	Mm.188709. Mm.451578.

Genome annotation databases

Ensemblⁱ	ENSMUST00000086444; ENSMUSP00000083633; ENSMUSG00000073557. ENSMUST00000168381; ENSMUSP00000131406; ENSMUSG00000073557.
GeneIDⁱ	329251.
KEGGⁱ	mmu:329251.
UCSC genome browser More...UCSCⁱ	uc007csm.1. mouse.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC117827 Genomic DNA. No translation available. AC131591 Genomic DNA. No translation available. BC145746 mRNA. Translation: AAI45747.1. CH466520 Genomic DNA. Translation: EDL39598.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001074776.1. NM_001081307.1. XP_006529772.1. XM_006529709.3.
UniGeneⁱ	Mm.188709. Mm.451578.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000086444; ENSMUSP00000083633; ENSMUSG00000073557. ENSMUST00000168381; ENSMUSP00000131406; ENSMUSG00000073557.
GeneIDⁱ	329251.
KEGGⁱ	mmu:329251.
UCSC genome browser More...UCSCⁱ	uc007csm.1. mouse.

Organism-specific databases

CTDⁱ	4660.
MGIⁱ	MGI:1916417. Ppp1r12b.

Phylogenomic databases

eggNOGⁱ	KOG0505. Eukaryota. COG0666. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000119141.
HOGENOMⁱ	HOG000290648.
HOVERGENⁱ	HBG052561.
KEGG Orthology (KO) More...KOⁱ	K12329.
OMAⁱ	EKHEPSA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0UPK.
TreeFamⁱ	TF105543.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000073557.

Bgeeⁱ

ENSMUSG00000073557.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00204. ANK. 1 hit.
Gene3Dⁱ	1.25.40.20. 3 hits.
InterProⁱ	View protein in InterPro IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR031775. PRKG1_interact.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF12796. Ank_2. 2 hits. PF15898. PRKG1_interact. 1 hit.
SMARTⁱ	View protein in SMART SM00248. ANK. 5 hits.
SUPFAMⁱ	SSF48403. SSF48403. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 4 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A6H644_MOUSE
Accessionⁱ	A6H644Primary (citable) accession number: A6H644
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	July 24, 2007
	Last sequence update:	July 24, 2007
	Last modified:	July 5, 2017
	This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB - A6H644 (A6H644_MOUSE)

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MCG130490

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Gene expression databases

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Domains and Repeats

Coiled coil

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A6H644 (A6H644_MOUSE)

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MCG130490

Ppp1r12b

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ