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Protein

GTPase HflX

Gene

hflX

Organism
Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi213MagnesiumUniRule annotation1
Metal bindingi233MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi206 – 213GTPUniRule annotation8
Nucleotide bindingi231 – 235GTPUniRule annotation5
Nucleotide bindingi252 – 255GTPUniRule annotation4
Nucleotide bindingi318 – 321GTPUniRule annotation4
Nucleotide bindingi364 – 366GTPUniRule annotation3

GO - Molecular functioni

Keywordsi

LigandGTP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciFPSY402612:G1GJP-2568-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase HflXUniRule annotation
Alternative name(s):
GTP-binding protein HflXUniRule annotation
Gene namesi
Name:hflXUniRule annotation
Ordered Locus Names:FP2414
OrganismiFlavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Taxonomic identifieri402612 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000006394 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: May associate with membranes.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004126571 – 413GTPase HflXAdd BLAST413

Proteomic databases

PRIDEiA6H294

Interactioni

Subunit structurei

Monomer. Associates with the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi402612.FP2414

Structurei

3D structure databases

ProteinModelPortaliA6H294
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini200 – 386Hflx-type GUniRule annotationAdd BLAST187

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1N Bacteria
COG2262 LUCA
HOGENOMiHOG000260368
KOiK03665
OMAiHPATYIG
OrthoDBiPOG091H0464

Family and domain databases

CDDicd01878 HflX, 1 hit
HAMAPiMF_00900 GTPase_HflX, 1 hit
InterProiView protein in InterPro
IPR030394 G_HFLX_dom
IPR032305 GTP-bd_M
IPR006073 GTP_binding_domain
IPR016496 GTPase_HflX
IPR025121 GTPase_HflX_N
IPR027417 P-loop_NTPase
PANTHERiPTHR10229 PTHR10229, 1 hit
PfamiView protein in Pfam
PF16360 GTP-bdg_M, 1 hit
PF13167 GTP-bdg_N, 1 hit
PF01926 MMR_HSR1, 1 hit
PIRSFiPIRSF006809 GTP-binding_hflX_prd, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03156 GTP_HflX, 1 hit
PROSITEiView protein in PROSITE
PS51705 G_HFLX, 1 hit

Sequencei

Sequence statusi: Complete.

A6H294-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEKETINFE KTIIVGIVTQ NQSEEKLKEY LDELEFLTFT AGGEVVKRFS
60 70 80 90 100
QKMERPNPKT FLGTGKIEEI NLYVLENGIS TIVFDDELTP SQQKNISKII
110 120 130 140 150
DCKILDRTHL ILDIFAQRAE TSYARTQVEL AQCIYLLPRL SGMWTHLERQ
160 170 180 190 200
KGGIGMRGPG ETEIETDRRI VRDRIALLKE KIKIIDKQQA TQRGNRGAMV
210 220 230 240 250
RVALVGYTNV GKSTLMNAVG KSDVFVENKL FATLDTTVRK VVIKNLPFLL
260 270 280 290 300
SDTVGFIRKL PTQLVDSFKS TLDEVREADL LLHVVDISHQ DFEDHIDAVN
310 320 330 340 350
KILLDIKSAD KPTIMVFNKI DAYKHLTIDA DDLMTERTSK HYTLQEWKNT
360 370 380 390 400
WMNKVGEQNA LFISATNKEN FEEFRKKVYE TVREIHITRF PYNKFLYPDY
410
EDAIDKEEEQ DQD
Length:413
Mass (Da):47,692
Last modified:July 24, 2007 - v1
Checksum:i1F43C3801251A3AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM398681 Genomic DNA Translation: CAL44468.1
RefSeqiWP_011964502.1, NC_009613.3
YP_001297269.1, NC_009613.3

Genome annotation databases

EnsemblBacteriaiCAL44468; CAL44468; FP2414
GeneIDi5299510
KEGGifps:FP2414
PATRICifig|402612.5.peg.2470

Similar proteinsi

Entry informationi

Entry nameiHFLX_FLAPJ
AccessioniPrimary (citable) accession number: A6H294
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: July 24, 2007
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health