A6H213 (SURE_FLAPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	FP2332

Organism

Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

Taxonomic identifier

402612 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335261
Sites
	Metal binding	11	1	Divalent metal cation By similarity
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	42	1	Divalent metal cation By similarity
	Metal binding	99	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A6H213 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 409BB36253EC1230	FASTA	257	28,207
	10 20 30 40 50 60 MSKPLILVTN DDGISAPGIR SLIAVMQEIG TVVVVAPDSP QSAMGHAITI NSTLHLNKIS 70 80 90 100 110 120 AENAAVTEYS CSGTPVDCVK LAVNEILKQK PDLCVSGVNH GSNSSINVIY SGTMSAAVEA 130 140 150 160 170 180 GIEGIPAIGF SLLDYDWNAD FETFKPYIKK IALEVLQKGL PDSVVLNVNF PKRKEEDLKG 190 200 210 220 230 240 IKICRQAKAM WEEKFDKRKT PQGKDYYWLT GEFVNHDKGE DTDEWALQNG YISVVPVQFD 250 MTAHHAIQAL NNWDLNK

References

[1]

"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum." Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A. Nat. Biotechnol. 25:763-769(2007) [PubMed: 17592475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM398681 Genomic DNA. Translation: CAL44387.1.
RefSeq	YP_001297188.1. NC_009613.1.
3D structure databases
ProteinModelPortal	A6H213.
ModBase	Search...
Protein-protein interaction databases
STRING	A6H213.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5299535.
GenomeReviews	Gene locus FP2332 in contig AM398681_GR.
KEGG	fps:FP2332.
NMPDR	fig|402612.4.peg.2288.
PATRIC	21909700. VBIFlaPsy4505_2386.
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	SINVIYS.
ProtClustDB	PRK00346.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_FLAPJ

Accession

Primary (citable) accession number: A6H213

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program