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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:FP1752
OrganismiFlavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Taxonomic identifieri402612 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium
Proteomesi
  • UP000006394 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003254971 – 496Probable malate:quinone oxidoreductaseAdd BLAST496

Interactioni

Protein-protein interaction databases

STRINGi402612.FP1752.

Structurei

3D structure databases

ProteinModelPortaliA6H0E6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

A6H0E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARQKIESDI VLIGAGIMSA TLGLLLKELN PKLKIEIFER LDIAAAESSD
60 70 80 90 100
AWNNAGTGHA AFCELNYTPE LEDGTIETKK ALKISEAFEV SRQLWTYLVE
110 120 130 140 150
KGLLQNPENF IKSVPHMSLV WGNDNVEYLR KRFEALQQFH LFKTMEFSDN
160 170 180 190 200
IEKIKEWAPL VMENRNSKDK IAATSMKLGT DVNFGTLTRN MFKYLETLEG
210 220 230 240 250
VTMHFNHDVY GLKKREDGRW RAKVKNIATG EKKKIFAPFV FIGAGGGSLL
260 270 280 290 300
LLEKANIPEG QGFGGFPVSG QWLKCTNPEV IQKHSAKVYG KASVGAPPMS
310 320 330 340 350
VPHIDTRMID GKKALLFGPY AGFSTKFLKN GSYFDLIKSI EFSNIKPMLG
360 370 380 390 400
AGVKNIPLTK YLIEQVIQSS DDRLKALKEY VPSAKKEDWV LENAGQRVQV
410 420 430 440 450
IKKDKDGHGI LEFGTEVVTA HDGSLAVLLG ASPGASTAVQ IMVDLITKCF
460 470 480 490
PEEVKTTIWQ NKLKEMIPSY GQSLNENTVL CDQIRAKTNE ILKLKV
Length:496
Mass (Da):55,264
Last modified:July 24, 2007 - v1
Checksum:iA958517280D79F00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM398681 Genomic DNA. Translation: CAL43819.1.
RefSeqiWP_011963862.1. NC_009613.3.
YP_001296626.1. NC_009613.3.

Genome annotation databases

EnsemblBacteriaiCAL43819; CAL43819; FP1752.
GeneIDi5300676.
KEGGifps:FP1752.
PATRICi21908448. VBIFlaPsy4505_1771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM398681 Genomic DNA. Translation: CAL43819.1.
RefSeqiWP_011963862.1. NC_009613.3.
YP_001296626.1. NC_009613.3.

3D structure databases

ProteinModelPortaliA6H0E6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi402612.FP1752.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL43819; CAL43819; FP1752.
GeneIDi5300676.
KEGGifps:FP1752.
PATRICi21908448. VBIFlaPsy4505_1771.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.
OrthoDBiPOG091H0B7C.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_FLAPJ
AccessioniPrimary (citable) accession number: A6H0E6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: July 24, 2007
Last modified: November 2, 2016
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.