A6H0E6 (MQO_FLAPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	FP1752

Organism

Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

Taxonomic identifier

402612 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 496	496	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325497

Sequences

	Sequence		Length	Mass (Da)
	A6H0E6 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: A958517280D79F00	FASTA	496	55,264
	10 20 30 40 50 60 MARQKIESDI VLIGAGIMSA TLGLLLKELN PKLKIEIFER LDIAAAESSD AWNNAGTGHA 70 80 90 100 110 120 AFCELNYTPE LEDGTIETKK ALKISEAFEV SRQLWTYLVE KGLLQNPENF IKSVPHMSLV 130 140 150 160 170 180 WGNDNVEYLR KRFEALQQFH LFKTMEFSDN IEKIKEWAPL VMENRNSKDK IAATSMKLGT 190 200 210 220 230 240 DVNFGTLTRN MFKYLETLEG VTMHFNHDVY GLKKREDGRW RAKVKNIATG EKKKIFAPFV 250 260 270 280 290 300 FIGAGGGSLL LLEKANIPEG QGFGGFPVSG QWLKCTNPEV IQKHSAKVYG KASVGAPPMS 310 320 330 340 350 360 VPHIDTRMID GKKALLFGPY AGFSTKFLKN GSYFDLIKSI EFSNIKPMLG AGVKNIPLTK 370 380 390 400 410 420 YLIEQVIQSS DDRLKALKEY VPSAKKEDWV LENAGQRVQV IKKDKDGHGI LEFGTEVVTA 430 440 450 460 470 480 HDGSLAVLLG ASPGASTAVQ IMVDLITKCF PEEVKTTIWQ NKLKEMIPSY GQSLNENTVL 490 CDQIRAKTNE ILKLKV

References

[1]

"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum." Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A. Nat. Biotechnol. 25:763-769(2007) [PubMed: 17592475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM398681 Genomic DNA. Translation: CAL43819.1.
RefSeq	YP_001296626.1. NC_009613.1.
3D structure databases
ProteinModelPortal	A6H0E6.
ModBase	Search...
Protein-protein interaction databases
STRING	A6H0E6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5300676.
GenomeReviews	Gene locus FP1752 in contig AM398681_GR.
KEGG	fps:FP1752.
NMPDR	fig|402612.4.peg.1691.
PATRIC	21908448. VBIFlaPsy4505_1771.
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	LEKEWAY.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_FLAPJ

Accession

Primary (citable) accession number: A6H0E6

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program