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A6GZP8 (SYR_FLAPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:FP1498
OrganismFlavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) [Reference proteome] [HAMAP]
Taxonomic identifier402612 [NCBI]
Taxonomic lineageBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeFlavobacterium

Protein attributes

Sequence length601 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 601601Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000018027

Regions

Motif133 – 14311"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A6GZP8 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 6EBFC96C78C39B51

FASTA60167,873
        10         20         30         40         50         60 
MSLQEILNPS IKTAIHQLFD LTIEKIEFQS TRKEFDGDIT MVIFPLLKLI KTPQATPNGA 

        70         80         90        100        110        120 
KLNPADLGNK IGNYLVENVA QVEAFNVVSG FLNIVIANDY YINFFNTIKT DAQFGFVSPS 

       130        140        150        160        170        180 
EHDKAIMVEY SSPNTNKPLH LGHVRNNLLG YSVAEIIKAS GKKVYKTQII NDRGIHICKS 

       190        200        210        220        230        240 
MLAWQKFGHS ETPETSGLKG DKLVGKYYVA FDKAYKVEIA ELMLQGKTEE EAKKQAPIII 

       250        260        270        280        290        300 
EAQQMLLDWE AGKPAVMALW KTMNQWVYDG FATTYKNLGV NFDSYYYESN TYLLGKEVVQ 

       310        320        330        340        350        360 
IGLDKGVFEK DPDGSVWIDL TQDGLDRKIV LRSDGTAVYM TQDIGTAIQR VKDFSDVGGM 

       370        380        390        400        410        420 
VYTVGNEQDY HFRVLFLILK KLGFDWASSL YHLSYGMVEL PSGKMKSREG TVVDADDLME 

       430        440        450        460        470        480 
EMTSTAQKLS EDLGKLESYS EEEKAILYKT IGLGALKYYI LKVDPKKSMM FNPEESVDFA 

       490        500        510        520        530        540 
GNTGPFIQYT YARIQSILRK ANFDITVTIS TKLHPKEKEL IKQIEMYPEV IQHAAANHSP 

       550        560        570        580        590        600 
ALIANYIYDL VKEYNSFYQT VSILGEEDND KKVFRVQLSK KVADTIKTAF TLLGIDVPER 


M 

« Hide

References

[1]"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum."
Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A.
Nat. Biotechnol. 25:763-769(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM398681 Genomic DNA. Translation: CAL43571.1.
RefSeqYP_001296380.1. NC_009613.3.

3D structure databases

ProteinModelPortalA6GZP8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING402612.FP1498.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL43571; CAL43571; FP1498.
GeneID5300803.
KEGGfps:FP1498.
PATRIC21907920. VBIFlaPsy4505_1512.

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247211.
KOK01887.
OMAYVKFHDE.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_FLAPJ
AccessionPrimary (citable) accession number: A6GZP8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: July 24, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries