A6GYI4 (A6GYI4_FLAPJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thymidine kinase HAMAP MF_00124 RuleBase RU000544
EC=2.7.1.21 HAMAP MF_00124 RuleBase RU000544

Gene names

Name:	tdk HAMAP MF_00124 EMBL CAL43157.1
Ordered Locus Names:	FP1063

Organism

Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

Taxonomic identifier

402612 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634
Subunit structure	Homotetramer By similarity. HAMAP MF_00124
Subcellular location	Cytoplasm By similarity HAMAP MF_00124.
Sequence similarities	Belongs to the thymidine kinase family. HAMAP MF_00124 RuleBase RU004165

Ontologies

Keywords
Biological process	DNA synthesis HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634
Cellular component	Cytoplasm HAMAP MF_00124
Ligand	ATP-binding HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00124 RuleBase RU000544 SAAS SAAS020634 EMBL CAL43157.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP thymidine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	21 – 28	8	ATP By similarity HAMAP MF_00124
	Nucleotide binding	93 – 96	4	ATP By similarity HAMAP MF_00124
Sites
	Active site	94	1	Proton acceptor By similarity HAMAP MF_00124

Sequences

	Sequence		Length	Mass (Da)
	A6GYI4 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: 5858A0C11E12CFF4	FASTA	202	22,748
	10 20 30 40 50 60 MFLENTVNHK EQFGWIEVIC GSMFSGKTEE LIRRLKRAQF AKQKVEIFKP TIDTRYDDEM 70 80 90 100 110 120 VVSHNKNEIR STPVPAAANI AILAQGCDVV GIDEAQFFDD EIVKICNDLA NSGIRVIVAG 130 140 150 160 170 180 LDMDFKGNPF GPMPALMATA EYVTKVHAVC TRTGNLANYS FRKTDNDKLV MLGETEEYEP 190 200 LSRAAYYNAM RENMIVKDAE HL

References

[1]

"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum." Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A. Nat. Biotechnol. 25:763-769(2007) [PubMed: 17592475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM398681 Genomic DNA. Translation: CAL43157.1.
RefSeq	YP_001295968.1. NC_009613.1.
3D structure databases
ProteinModelPortal	A6GYI4.
ModBase	Search...
Protein-protein interaction databases
STRING	A6GYI4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5298800.
GenomeReviews	Gene locus FP1063 in contig AM398681_GR.
KEGG	fps:FP1063.
NMPDR	fig|402612.4.peg.1033.
PATRIC	21907012. VBIFlaPsy4505_1077.
Phylogenomic databases
eggNOG	COG1435.
HOGENOM	HBG522108.
OMA	EPRCRHH.
ProtClustDB	PRK04296.
Family and domain databases
HAMAP	MF_00124. Thymidine_kinase. [Tree]
InterPro	IPR001267. Thymidine_kinase. IPR020634. Thymidine_kinase_subgr. [Graphical view]
KO	K00857.
PANTHER	PTHR11441. TK_cell. 1 hit.
Pfam	PF00265. TK. 1 hit. [Graphical view]
PIRSF	PIRSF035805. TK_cell. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A6GYI4_FLAPJ

Accession

Primary (citable) accession number: A6GYI4

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)