A6GWH9 (A6GWH9_FLAPJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209

Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209

Gene names

Name:	ppa HAMAP MF_00209 EMBL CAL42452.1
Ordered Locus Names:	FP0339

Organism

Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

Taxonomic identifier

402612 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length	176 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Diphosphate + H2O = 2 phosphate. HAMAP MF_00209
Cofactor	Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209
Subcellular location	Cytoplasm By similarity HAMAP MF_00209.
Sequence similarities	Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00209
Ligand	Magnesium HAMAP MF_00209 Metal-binding HAMAP MF_00209
Molecular function	Hydrolase HAMAP MF_00209 EMBL CAL42452.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	phosphate-containing compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	inorganic diphosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	58	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	63	1	Magnesium 1 By similarity HAMAP MF_00209
	Metal binding	63	1	Magnesium 2 By similarity HAMAP MF_00209
	Metal binding	95	1	Magnesium 1 By similarity HAMAP MF_00209

Sequences

	Sequence		Length	Mass (Da)
	A6GWH9 [UniParc]. Last modified July 24, 2007. Version 1. Checksum: AEC177590AA9AE79	FASTA	176	20,140
	10 20 30 40 50 60 MTTDKIETFD VLVEIPRGSR NKYEYDFDLK RMRFDRMLFS SMMYPADYGF IPETLALDGD 70 80 90 100 110 120 PLDVLVLLTK PTFPGCVIEV KPIGIFNMAD DKGQDEKIIC VPVSDPIWNS LNDLSDINAH 130 140 150 160 170 LVKEIEHFFQ VYKDLENKKV EVKGWGDVKE AKEIIAQCVA RFQAIENKPA GLFSIK

References

[1]

"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum." Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A. Nat. Biotechnol. 25:763-769(2007) [PubMed: 17592475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM398681 Genomic DNA. Translation: CAL42452.1.
RefSeq	YP_001295270.1. NC_009613.1.
3D structure databases
ProteinModelPortal	A6GWH9.
ModBase	Search...
Protein-protein interaction databases
STRING	A6GWH9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5300121.
GenomeReviews	Gene locus FP0339 in contig AM398681_GR.
KEGG	fps:FP0339.
NMPDR	fig|402612.4.peg.334.
PATRIC	21905524. VBIFlaPsy4505_0350.
Phylogenomic databases
eggNOG	COG0221.
HOGENOM	HBG529150.
OMA	PNDFNVI.
ProtClustDB	CLSK851274.
Family and domain databases
HAMAP	MF_00209. Inorganic_PPase. [Tree]
InterPro	IPR008162. Pyrophosphatase. [Graphical view]
Gene3D	G3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KO	K01507.
PANTHER	PTHR10286. Pyrophosphatase. 1 hit.
Pfam	PF00719. Pyrophosphatase. 1 hit. [Graphical view]
SUPFAM	SSF50324. Pyrophosphatase. 1 hit.
PROSITE	PS00387. PPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A6GWH9_FLAPJ

Accession

Primary (citable) accession number: A6GWH9

Entry history

Integrated into UniProtKB/TrEMBL:	July 24, 2007
Last sequence update:	July 24, 2007
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)