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A6GWD9 (F16PA_FLAPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1
Short name=FBPase class 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name:fbp
Ordered Locus Names:FP0299
OrganismFlavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)
Taxonomic identifier402612 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Flavobacteriaceae › Flavobacterium

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 335335Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000364556

Regions

Region120 – 1234Substrate binding By similarity

Sites

Metal binding931Magnesium 1 By similarity
Metal binding1171Magnesium 1 By similarity
Metal binding1171Magnesium 2 By similarity
Metal binding1191Magnesium 1; via carbonyl oxygen By similarity
Metal binding1201Magnesium 2 By similarity
Metal binding2801Magnesium 2 By similarity
Binding site2131Substrate By similarity
Binding site2441Substrate By similarity
Binding site2741Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
A6GWD9 [UniParc].

Last modified July 24, 2007. Version 1.
Checksum: 2A81F5C96AD99FA9

FASTA33537,321
        10         20         30         40         50         60 
MEERNKTLGE FIIENQQSFQ YSSGELSRII NSIRLAAKVV NYKVNKAGLV DIVGAAGEQN 

        70         80         90        100        110        120 
IQGEDQQKLD VYANEIFIQT LINREIVCGI ASEENDDFIT VAGSDNSHNN KYVVLMDPLD 

       130        140        150        160        170        180 
GSSNIDVNVS VGTIFSVFRR ITPVGTPVTI EDFLQPGINQ VAAGYVIYGT STMLVYTTGD 

       190        200        210        220        230        240 
GVNGFTLNPA IGTFYLSHPN MKYSKDGHIY SMNEGNYVHF PQGVKNYIKY CQSEEGDRPY 

       250        260        270        280        290        300 
TSRYIGSLVS DFHRNMIKGG IYIYPTSSKA PKGKLRLLYE CSPMAFIAEQ AGGKASDGYN 

       310        320        330 
RIMEIQPTEL HQRVPFFCGS YNMVEKAEEF MKNTK

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References

[1]"Complete genome sequence of the fish pathogen Flavobacterium psychrophilum."
Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B., Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F., Claverol S., Dumetz F., Le Henaff M., Benmansour A.
Nat. Biotechnol. 25:763-769(2007) [PubMed: 17592475] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JIP02/86 / ATCC 49511.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AM398681 Genomic DNA. Translation: CAL42412.1.
RefSeqYP_001295230.1. NC_009613.1.

3D structure databases

ProteinModelPortalA6GWD9.
SMRA6GWD9. Positions 6-332.
ModBaseSearch...

Protein-protein interaction databases

STRINGA6GWD9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5298899.
GenomeReviewsGene locus FP0299 in contig AM398681_GR.
KEGGfps:FP0299.
NMPDRfig|402612.4.peg.295.
PATRIC21905448. VBIFlaPsy4505_0312.

Phylogenomic databases

eggNOGCOG0158.
HOGENOMHBG731261.
OMAHWEAPVQ.
ProtClustDBPRK09293.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16PA_FLAPJ
AccessionPrimary (citable) accession number: A6GWD9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: July 24, 2007
Last modified: December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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